| November 12, 2017 |
summary |
The aim of this study is evaluation of effect of Curcumin on the serum levels of 12-inflammatory cytokines and highly sensitive C-reactive protein (hsCRP) level in the patients with non- alcoholic fatty liver. Study is designed as Randomized, double-blind trial. Examples include patients referred to Clinic of 22 Bahaman Hospital in Neyshabur city that disease has been confirmed by ultrasound examination and liver enzyme levels. 86 patients (age 15-60) are selected and will be divided into two groups. Exclusion criteria are included: enhancing drugs liver enzymes;malabsorption syndrome; steroid use; heart and lung disease; regnant and lactating women; diabetic patients; triglycerides over 150mg/dl; hypothyroidism and hyperthyroidism; hepatitis B and C; Wilson\'s disease; celiac disease; deficiency of alpha-1 antitrypsin and alcohol consumption. Patients were randomly divided into two groups and intervention are performed for 3 months, treated with a single dose of 80 mg per day curcumin or placebo. At the beginning and end of the study, blood levels of the 12 inflammatory cytokines and hsCRP will be evaluated.
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