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Study aim
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This study is a parallel clinical trial with the aim of evaluating honey and ozone therapy on diabetic foot ulcers.
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Design
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A sample of 70 patients with diabetic patients admitted to the hospital in Kermanshah city. In this research, a random allocation method is used. People undergoing omental and curative therapy. In the group of honey therapy, 35 people will be replaced every 3-7 days of dressing and will continue for up to 4 weeks. In the ozone therapy group, 35 patients will be treated using topical ozone gas and intravenous injection Patients are used. Wound healing is based on the PEDIS table and the method of measuring the wound is using a graded ruler. In the course of the study, the wound is measured and recorded. At the end of the wound, each wound is compared with each other.
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Settings and conduct
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This study, which is a sucrose study, is carried out at Bistoon Hospital in Kermanshah. First, 70 nephrologists were studied and randomly divided into two groups of 35 and interventions were performed
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Participants/Inclusion and exclusion criteria
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Inclusion criteria:.
1. Diabetic patients have grade 3 or 4 renal insufficiency.
2. Patients should be admitted to Bisotun Hospital.
3. Patients between 20-75 years of age.
4. Patients undergo routine treatment
Exit criteria:
1. Patients who receive another treatment at the same time.
2. Patients who did not complete the treatment period and were not regular.
3. Patients whose feet require surgical debridement.
4. Patients who die during the study.
5. Patients who are not satisfied with the continuation of treatment.
6. There is a history of deep vein thrombosis
7. There is a history of hemorrhage from the foot
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Intervention groups
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The study is divided into two intervention groups of ozone and honey therapy. After the selection, participants are placed in one of the two groups:
Patients who have received routine treatment in the honey therapy group. After wounding with normal saline, the honey dressing manufactured by HydroTac, Germany, wound on the wound, the size of the dressing depends on the size of the wound. This dressing is carried out 3-7 days once and forty-four weeks, which is first taught by the researcher, and other necessary arrangements will be made by the client or his family.
Patients in the ozone therapy group receiving routine treatment, after ozone wound healing with normal saline, an ozonotherapy is performed, 8 times for each patient for 8 weeks of ozone therapy.
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Main outcome variables
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Diabetic foot ulcer ؛ Every 3 to 7 days, once a week, 4 weeks in the honey therapy group & 2 times a week for 4 weeks in the ozone therapy group.