Comparing the Efficacy of Meta-Cognitive and Cognitive-Behavioral Therapy on Obsession and Compulsion symptoms of Patients with Obsessive-Compulsive Disorder (OCD)
The Aim of this study is to compare key aspects of cognitive-behavioral model and meta-Cognitive therapy model for the treatment of obsessive-compulsive disorder and reducing secondary symptoms of OCD (such as anxiety, depression, emotional regulation, quality of life and functional) in addition to the disease's symptoms.
Inclusion criteria were having a diagnosis of obsessive-compulsive disorders, aged between 20 to 50 years old, the consent of the subjects and completed consent form to participate in research and exclusion criteria were having simultaneously diagnosis of psychotic disorders, major depressive disorder, bipolar disorder , substance use disorders, alcohol and drug abuse, personality disorders and receiving the same simultaneously psychotherapy. The study population is 22 patients with obsessive-compulsive disorders, 20 to 50 year old men and women who were referred for OCD treatment are randomly assigned to two treatment groups. Two models of cognitive-behavioral treatment protocol based on the Clark (2004) and meta-cognitive therapy based on treatment protocol of Wels (2009) in 10 individual sessions. Results are compared in pre/post-test and follow-up. This comparison is based on a progressive model for clinical research from psychological treatment and Berkowitz and Gras. This could be the first step in comparison meta-cognitive approach cognitive-behavioral approach in OCD.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2015012220728N1
Registration date:2015-05-16, 1394/02/26
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2015-05-16, 1394/02/26
Registrant information
Name
Sepideh Rajezi Esfahani
Name of organization / entity
Behavioral Sciences Research Center of Shahid Beheshti University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 7755 3034
Email address
s.rajezi@sbmu.ac.ir
Recruitment status
Recruitment complete
Funding source
Behavioral Sciences Research Center of Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Expected recruitment start date
2015-03-31, 1394/01/11
Expected recruitment end date
2015-09-30, 1394/07/08
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparing the Efficacy of Meta-Cognitive and Cognitive-Behavioral Therapy on Obsession and Compulsion symptoms of Patients with Obsessive-Compulsive Disorder (OCD)
Inclusion criteria: Having a diagnosis of obsessive-compulsive disorder, based on semi-structured interview SCID-I; Having aged between 20 to 50 years old; The consent of subjects, and completing the ethical consent form to participate in a research study.
Exclusion Criteria: Having a concurrent diagnosis of psychotic disorders, major depressive disorder, bipolar disorder, neurological disorders that cause similar symptoms as OCD, substance abuse, alcohol and drugs abuse, Sever personality disorders; The need for psychiatric emergencies; Get medication and other drugs in relation to other psychological problems simultaneously with the present study.
Age
From 18 years old to 50 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
22
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Shahid Beheshti University of Medical Sciences
Street address
Iran, Tehran Velenjak St. , Shahid Chamran Highway
City
Tehran
Postal code
Approval date
2015-02-14, 1393/11/25
Ethics committee reference number
102-13599
Health conditions studied
1
Description of health condition studied
Obsessive-compulsive disorder
ICD-10 code
ّF 42
ICD-10 code description
The essential feature is recurrent obsessional thoughts or compulsive acts. Obsessional thoughts are ideas, images, or impulses that enter the patient's mind again and again in a stereotyped form. They are almost invariably distressing and the patient oft
Primary outcomes
1
Description
severity of obsessive thoughts
Timepoint
Before the intervention, in the middle of intervention, after intervetion (three months after intervention), a month after intervention
Method of measurement
Yale Brown scale (Y-BOCS)
2
Description
compulsive severity
Timepoint
Before the intervention, in the middle of intervention, after intervetion (three months after intervention), a month after intervention
Method of measurement
Y-BOCS symptom severity checklist
3
Description
cognition
Timepoint
Before the intervention, in the middle of intervention, after intervetion (three months after intervention), a month after intervention
Method of measurement
OBQ
4
Description
Metacognition
Timepoint
Before the intervention, in the middle of intervention, after intervetion (three months after intervention), a month after intervention
Method of measurement
MCQ
Secondary outcomes
1
Description
Anxiety
Timepoint
Before the intervention, in the middle of intervention, after intervetion (three months after intervention), a month after intervention
Method of measurement
Anxiety- BAI
2
Description
depression
Timepoint
Before the intervention, in the middle of intervention, after intervetion (three months after intervention), a month after intervention
Method of measurement
depression- BDI
3
Description
emotional regulation
Timepoint
Before the intervention, in the middle of intervention, after intervetion (three months after intervention), a month after intervention
Method of measurement
emotional regulation- DERS
4
Description
quality of life
Timepoint
Before the intervention, in the middle of intervention, after intervetion (three months after intervention), a month after intervention
Method of measurement
WHOQOL
5
Description
function
Timepoint
Before the intervention, in the middle of intervention, after intervetion (three months after intervention), a month after intervention
Method of measurement
WHO DAS 2.0
Intervention groups
1
Description
CBT for OCD, protocol D.Clarck (2004)
there will be 10 sessions and each session is 1 hour.
Category
Treatment - Other
2
Description
MCT for OCD, Protocol A.Wells (2009)
there will be 10 sessions and each session is 1 hour.
Category
Treatment - Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Private and public psychiatric clinic
Full name of responsible person
Street address
City
Tehran
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Behavioral Sciences Research Center of Shahid Beheshti University of Medical Sciences
Full name of responsible person
shiam Ghanbari
Street address
Iran, Tehran Velenjak St. , Shahid Chamran Highway
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Behavioral Sciences Research Center of Shahid Beheshti University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Behavioral Sciences Research Center of Shahid Beheshti University of Medical Sciences
Full name of responsible person
sepideh rajezi
Position
PhD candidate of clinical psychology
Other areas of specialty/work
Street address
Iran, Tehran Velenjak St. , Shahid Chamran Highway
City
Tehran
Postal code
Phone
+98 21 7755 3074
Fax
Email
Sepideh.rajezi@gmail.coms.rajezi@sbmu.ac.ir
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Behavioral Sciences Research Center of Shahid Beheshti University of Medical Sciences , Tehran, Iran