Comparison of four types of aerobic, resistance, combined (Aerobic - Resistance) and High-intensity interval exercise on coagulation factors (platelets, PT, PTT, and fibrinogen) and fibrinolysis (D-dimer) in healthy untrained young men
The aim of this study was to examine the effect of aerobic training, resistance, concurrent (aerobic-resistance) training and high intensity interval training (HIIT) on coagulation and fibrinolysis in healthy young men non-athletes. Methods: An experimental study and sampling was easy or available.concurrent (aerobic-resistance) training, HIIT control will be divide in 3 groups . Groups training will be exercise for three times in a week for 8 weeks. Blood samples 24 hours before the first training session, 30 minutes after the first and last training session and then 24 hours after the last training session collect for the evaluation clotting index; platelet counts , fibrinogen, PT, PTT and fibrinolysis index; D-dimer. The anthropometric variables and feeding people before the start of the study are recorded.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2016021726608N1
Registration date:2016-03-14, 1394/12/24
Registration timing:retrospective
Last update:
Update count:0
Registration date
2016-03-14, 1394/12/24
Registrant information
Name
Amir Amini
Name of organization / entity
Baqiyatallah University of Medical Science
Country
Iran (Islamic Republic of)
Phone
+98 21 8248 2402
Email address
amiramini@ut.ac.ir
Recruitment status
Recruitment complete
Funding source
the financial support of Vice Chancellor for the University of Baqiyatallah Medical Sciences, Iran
Expected recruitment start date
2014-04-21, 1393/02/01
Expected recruitment end date
2014-09-23, 1393/07/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of four types of aerobic, resistance, combined (Aerobic - Resistance) and High-intensity interval exercise on coagulation factors (platelets, PT, PTT, and fibrinogen) and fibrinolysis (D-dimer) in healthy untrained young men
Public title
The effects of different exercises on the prevention of thrombosis
Purpose
Basic scienece
Inclusion/Exclusion criteria
Inclusion criteria:
non smoking- Avoiding the use of drugs or alcohol- Lack of physical activity at least six months before the start of the study
exclusion criteria:
control group should not exercised
Age
From 20 years old to 30 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
50
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Random people using sealed envelopes are divided in different groups
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of Baqiyatallah University of Medical Sciences
Other disorders of circulatory system in diseases classified elsewhere
Primary outcomes
1
Description
platelet count, fibrinogen, PT, PTT and D-dimer
Timepoint
24 h Before and 30 min after one session and last of exercise, 24 h after last of exercise blood samples will obtain
Method of measurement
for evaluate fibrinogen (mg/dl), D-dimer (mg/dl), prothrombin time (PT), partial thromboplastin time (PTT) and platelet count (×1000/µl) from ELISA will use.
Secondary outcomes
1
Description
nutrition, anthropometric variables
Timepoint
24 h before and after intervention
Method of measurement
questionnaire and Tools specific to each indicator
Intervention groups
1
Description
Intervention group 3: high intensity interval training for Two months
Category
Prevention
2
Description
Intervention group 1: aerobic training for Two months
Two months
Category
Prevention
3
Description
Intervention group 2: resistance training for Two months
Category
Prevention
4
Description
Intervention group 3: concurrent training (combined aerobic with resistance training) for Two months
Category
Prevention
5
Description
control group: lack of physical activity during 2 month study
Category
Prevention
Recruitment centers
1
Recruitment center
Name of recruitment center
Exercise Physiology Research Center, Baqiyatallah University of Medical Science