Comparison of blood flow restriction strength training and traditional strength training on myostatin, muscle mass and some physiological factors in middle-age women
Objectives: The purpose of this study is to compare the effect of strength training with blood flow restriction and traditional strength training on myostatin, muscular mass and some related-muscle physiological factors in middle-age women.
Design: A semi-experimental study and pretest and post test design with two experimental groups and a control group, 29 healthy middle-age female voluntarily participated in study.
Setting and contact: Subjects were randomly assigned into three groups: blood flow restriction strength training, traditional strength training and control. The training program performed for eight weeks and three times per week. Strength, muscular mass and blood samples were measured before and after the exercise training. Participants including major eligibility criteria were physical healthy and aged 45 through 55 and excluding major eligibility criteria were illness and blood pressure above 14/10. Intervention: 8 weeks of strength training with blood flow restriction and traditional strength training. Main outcome measures: myostatin, muscular mass, stretgh.
General information
Acronym
Effect of strength training with and without blood flow restriction on myostatin and some physiologi
IRCT registration information
IRCT registration number:IRCT2017092736459N1
Registration date:2017-11-06, 1396/08/15
Registration timing:retrospective
Last update:
Update count:0
Registration date
2017-11-06, 1396/08/15
Registrant information
Name
Amin Farzaneh Hesari
Name of organization / entity
Sari Azad University
Country
Iran (Islamic Republic of)
Phone
+98 17 3222 8377
Email address
af.hessari@gmail.com
Recruitment status
Recruitment complete
Funding source
investigator
Expected recruitment start date
2016-06-21, 1395/04/01
Expected recruitment end date
2016-08-31, 1395/06/10
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of blood flow restriction strength training and traditional strength training on myostatin, muscle mass and some physiological factors in middle-age women
Public title
Comparison of two strength training on some muscular factors in middle-age women
Purpose
Other
Inclusion/Exclusion criteria
Including major criteria: healthy; 45 to 55years old.
Excluding major criteria: illness; blood pressure.
Age
From 42 years old to 50 years old
Gender
Female
Phase
2
Groups that have been masked
No information
Sample size
Target sample size:
29
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
The subjects were randomly divided in two experimental groups and a control group by random number table.
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
ethics committee of Sari Azad university
Street address
48161-19318, Sari Azad University, Farah Abad Rd, Sari
City
Sari
Postal code
Approval date
2016-11-03, 1395/08/13
Ethics committee reference number
IRIAU.SARI.REC.1395.8
Health conditions studied
1
Description of health condition studied
healthy related factors
ICD-10 code
Z00-Z13
ICD-10 code description
Factors influencing health status and contact with health services
Primary outcomes
1
Description
Myostatin
Timepoint
before and after of training
Method of measurement
Human Myostatin kits, ELIZA
2
Description
muscular mass
Timepoint
before and after of training
Method of measurement
measuring of thigh circumference
Secondary outcomes
1
Description
muscular strength
Timepoint
before and after tarining
Method of measurement
one repetition maximum
Intervention groups
1
Description
traditional strength training: 8 weeks and 3 times per week, intensity of 65-80% 1RM.
Category
Other
2
Description
blood flow restriction strength training: 8 weeks and 3 times per week, intensity of 20-30% 1RM.
Category
Other
3
Description
control group: without intervention
Category
N/A
Recruitment centers
1
Recruitment center
Name of recruitment center
Sari Azad University
Full name of responsible person
Amin Farzaneh Hesari
Street address
49161-19318, Azad University, Farah Abad Rd, Sari
City
Sari
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Vice chancellor for research, Sari Azad University
Full name of responsible person
Mohammad Farsi
Street address
Sari Azad University, Farah Abad Rd, Sari
City
Sari
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice chancellor for research, Sari Azad University
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Sari Azad University
Full name of responsible person
Amin Farzaneh Hesari
Position
Assistant Professor
Other areas of specialty/work
Street address
Islamic Azad university, Farah Abad Rd, Sari
City
Sari
Postal code
Phone
+98 11 3317 5112
Fax
Email
af.hessari@gmail.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Sari Azad university
Full name of responsible person
Amin Farzaneh Hesari
Position
Assistant Professor
Other areas of specialty/work
Street address
Islamic Azad university, Farah Abad Rd, Sari
City
Sari
Postal code
Phone
+98 11 3317 5112
Fax
Email
af.hessari@gmail.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Sari Azad University
Full name of responsible person
Amin Farzaneh Hesari
Position
assisstant professor
Other areas of specialty/work
Street address
Azad Unniversity, Farah Abad Rd, Sari
City
Sari
Postal code
Phone
+98 11 3317 5112
Fax
Email
af.hessari@gmail.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)