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Study aim
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The effect of the Active And Passive Humidifiers On The Parameters Of Pulmonary And Ventilator Associated Pneumonia In Patients Admitted To Intensive Care Units.
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Design
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In this study, 80 patients are selected under mechanical ventilation and are eligible to enter the study. Then, patients were randomly divided into two control and intervention groups.
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Settings and conduct
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Patients admitted to the ICU in the Ayatollah Mousavi Hospital affiliated to Zanjan University of Medical Sciences who have artificial airway were selected by convenience sampling metho .Initial sampling was done in random sampling by pilot method. Because of the sampling method and all the intervention methods in pilot sampling, as in the main samples, pilot samples were also considered as the main samples. After initial analysis of the results and using the formula, the final number of samples in both experimental and control groups was estimated to be approximately 80 patients
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Participants/Inclusion and exclusion criteria
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Inclusion criteria: Patients undergoing mechanical ventilation following 12 hours of intubation and mechanical ventilation and undergo mechanical ventilation during the study; Having vital signs in the normal range, not using dopamine, double-breasted or nitroglycerin, and hypotensive drugs؛ Patients should not have artificial teeth; Patients aged 18-60 years old; Modem of the ventilator is SIMV and the size of the tracheal tube is 7 to 8; patients have history of pneumonia, aspiration, chemotherapy, pulmonary injury in the lower airways, exacerbated myasthenia grave and recent MI; A pregnant woman is not pregnant or burn7;
Exclusion criteria: Patients who take pentoprazole instead of ranitidine; Age over 60 years; Chronic pulmonary disease; Having a chest tube and a pulmonary canine; Patients diagnosed with burns
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Intervention groups
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After receiving the letter of the Ethics Committee from the University of Medical Sciences and introducing the letter to the hospital authorities, the study began on February 20, 2017 in ICU department of Ayatollah Mousavi Hospital. Inhibitory interventions using the HME for the first group and the active Humidity type (HHS) were used for the second group. This intervention begins on the first day of admission to the intensive care unit for patients undergoing mechanical ventilation and is monitored for up to seven days, and daily pulmonary parameters and pneumonia rates are measured and recorded in both groups. In this study, the pulmonary parameters are included in the volume of air flow and airway resistance, the volume of emergency storm and exhalation, small airways, airway pressure and lung compilation, which is measured by ventilation device. For pneumonia caused by a ventilator, CPIS is calculated through variables such as the number of white blood cells, the amount of blood oxygenation saturated (calculated based on PaO2 divided into respiration oxygen) and chest radiography. In this study, premature VAP (less than 96 hours) and late VAP (greater than 96 hours) were studied. The samples were followed up to seven days, and in the first, third, and seventh day at night shift, pneumonia was evaluated using the CPIS scale. The scores were accumulated in each day; if a score of six or more was obtained, the diagnosis of pneumonia was definite. In order to determine the VAP, the temperature of the pedicle was calculated and, for determining the central temperature, the value was calculated to be 0.6 to the temperature To measure the temperature, the average of the same day's temperature was used for diagnosis. Diagnosis of all CPIS cases except the pulmonary infiltrates by itself. The jaws were performed and the graphic interpretation of the lungs was handled by an ICU practitioner (ICU specialist).
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Main outcome variables
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Respiratory rate, airway resistance increased in inactive Humidifier group. There was no significant difference in the level of pneumonia between the two groups.