Comparison of Cordia Myxa,s herbal syrup and Diphenhydramine in the treatment of dry cough

A Comparative Study on the Effect of Cordia Myxa,s herbal syrup and Diphenhydramine Syrup on the Treatment of Dry Coughing Patients

To compare the intervention and control groups, we divided Abuzar Hospital patients to 62 member groups who are given Cordia myxa΄s herbal syrup and Diphenhydramine compound respectively.

Patients with dry cough referred to Abouzar Children's Hospital by dividing them into two intervention and control groups and receiving the relevant drug that the researcher and the volunteer participated in this study are completely unaware until the last stage of extracting the final information. The Diphenhydramine and Cordia Myxa,s herbal syrup have the same appearance. Two syrups at a dose of 5 mg / kg / day are given in four divided doses. After 72 hours of the initial visit, the number and severity of the patients' night and day cough are compared with the first day.

Inclusion criteria: - Children aged 6-12 years, with acute cough and without foreign body aspiration along with mild fever, rhinorrhea, sneezing, mild sore throat, mild headache, mild nasal obstruction, hoarseness and conjunctivitis. Excusion criteria: 1- The existence of bacterial infection of the upper respiratory tract, mild fever to severe fever, sore throat, nausea, vomiting, abdominal pain and severe headaches 2- Inferior respiratory tract infections, cough, shortness of breath, malaise, chest pain, and Tachypnea 3- Drug intake before referral arbitrarily 4- Start the symptoms of otitis or sinusitis 5- Start the symptoms of lower respiratory problems 6- Avoid using recommended treatments 7- Add another drugs to the recommended treatment

Intervention group: Diphenhydramine Compound Control group: Cordia Myxa,s herbal syrup

dry cough condition

At first, both Diphenhydramine and Cordia Myxa,s herbal syrup are packed in the same boxes. Different serial numbers are placed on the boxes where the medications can be separated. We use simple randomization model using random number table (computer randomization method). The advantages of this kind of randomization are that the type of treatment allocated to the two groups is totally unpredictable and, according to the theory of probabilities, it can be guaranteed that in a large number, the sample size of the study will be similar in the intervention and control groups. It should be noted, that the implementation of this method is very simple. Since we have a complete list of elements that constitute the population, we use individual sampling. In this research, we use a randomized numbers table as randomization method, which is a computational method for generating a sequence of numbers that do not have a specific pattern. A random number is a mode of possible state that is selected during a random event. This method starts with a random initial number (core). Then we put this number into power 2 and select its middle numbers. The number of selected numbers is equal to the number of core digits. Then, after putting the zero point at the beginning of the generated middle number, the random number is obtained and according to the specific mathematical algorithm, the sequence numbers are generated. Any number is independent from other numbers.

the researcher and the volunteer participate in this study are completely unaware of the final stage of extracting the final information from the drugs that are presented separately by the pharmacist which are identical in appearance were placed in identical bottles.

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