Comparison of the effect of 8 weeks aerobic exercise and supplementation of green coffee on serum myonectin, methionine-like and insulin resistance in obese women
Purpose of this research is to compare the effects of aerobic exercises and green coffee consumption as a supplement on METTEORIN - LIKE and Myonectin level and Insulin resistance of obese women in Isfahan.
Design
Clinical work. Simple random Four groups of control /green coffee / intralum / combined with 40 patients were selected for two months
Settings and conduct
Anthropometric indices including height, weight, body fat percentage and body mass index were measured with minimum dress and no shoe. The weight of the subjects was measured with a German scale of 0.1 kg precision and their height was measured by tape measure with accuracy of 0.5 cm. The body mass index (BMI) was calculated by dividing the body weight (kg) by height (square meter). The percentage of subjects' fat was measured using the SAEHAN-SH 5020 calipers made in the UK using subcutaneous fat and using the method Three points (three-headed arm, abdomen, and supra) were calculated on the right side of the body after placement in the general equation of Pollack Jackson and to determine the percentage of fat in women
Participants/Inclusion and exclusion criteria
Requirement to enter healthy participants and not to use coffee and physical activity up to six months ago.
Intervention groups
Intervention group 1: Interval Training
Intervention group 2: Green coffee consumption
Intervention group 3: Interval training and green coffee consumption
Control group: No intervention
Main outcome variables
serum myonectin, methionine-like
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20170510033909N5
Registration date:2019-07-30, 1398/05/08
Registration timing:retrospective
Last update:2019-07-30, 1398/05/08
Update count:0
Registration date
2019-07-30, 1398/05/08
Registrant information
Name
فرزانه تقیان
Name of organization / entity
دانشگاه آزاد اسلامی.واحد اصفهان
Country
Iran (Islamic Republic of)
Phone
+98 913 308 0241
Email address
f.taghian@khuisf.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2018-12-22, 1397/10/01
Expected recruitment end date
2019-01-20, 1397/10/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of the effect of 8 weeks aerobic exercise and supplementation of green coffee on serum myonectin, methionine-like and insulin resistance in obese women
Public title
Investigating the effect of exercise and green coffee on reducing obesity
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Age range of 30 to 35 years
BMI> 30
Exclusion criteria:
Take an intervention to lose weight in the last year
Lack of participation in athletic exercises for at least the last six months
Lack of structural and abnormalities
No history of any Fractures and surgery in the last 1 year
Lack of cardiovascular, renal, hormonal and liver disease
Lack of menopause
Age
From 30 years old to 35 years old
Gender
Female
Phase
3
Groups that have been masked
No information
Sample size
Target sample size:
60
Randomization (investigator's opinion)
Randomized
Randomization description
Simple randomization , Random number table ،
To use random numbers, the researcher first predefines the reader for reading table numbers (for example, up, down, left, or right), the second is to consider numbers for different groups (for example, pair numbers for intervention A and individual numbers for Intervention B, another way of taking numbers from 2400 to intervene A, and numbers 25-49 for intervention B, are numbers 74-50 for group C and numbers 99-75 for group D), then put on one of the numbers and In one direction, it has been predefined and recorded numbers and allocated to different groups.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Factorial
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of najafabad University
Street address
Islamic Azad University-Najaf Abad Branch, Isfahan, Najaf Abad, University Blvd.
City
Isfahan,Najafabad
Province
Isfehan
Postal code
81838-95153
Approval date
2017-12-31, 1396/10/10
Ethics committee reference number
IR.IAU.NAJAFABAD.REC.1396.26
Health conditions studied
1
Description of health condition studied
obesity
ICD-10 code
E66
ICD-10 code description
Overweight and obesity
Primary outcomes
1
Description
Myonectin
Timepoint
At the beginning and end of the study after 8 weeks
Method of measurement
Serum concentration of Mayonectin by ELISA method using the Hangzhou Sbiofarm manufacturing kit in China
2
Description
Methionine-like
Timepoint
At the beginning and end of the study after 8 weeks
Method of measurement
Serum concentration of Mayonectin by ELISA method using the Hangzhou Sbiofarm manufacturing kit in China
Secondary outcomes
1
Description
Serum insulin concentration
Timepoint
Before and after intervention
Method of measurement
Serum insulin concentration by ELISA method and use of special kit, Monobind Inc., USA) (75 μg / ml micro-unit per ml, intra-group variation coefficient of 6.3%),
Intervention groups
1
Description
Intervention group: First intervention group: Interval exercise, which includes three sessions per week each session for an eight-week session
Category
Treatment - Other
2
Description
Intervention group 2 : Green coffee consumption , Participants in the group received green coffee supplement for 8 weeks and received 400 mg daily as 2 capsules of 200 mg.
Category
Rehabilitation
3
Description
Intervention group 3: Interval exercises and green coffee consumption Interval exercise, which included three sessions per week for one session for 8 weeks and a green tea supplement for 8 weeks and 400 mg daily for 2 capsules of 200 mg
Category
Rehabilitation
4
Description
Control group: Without intervention, they were only tracked
Category
N/A
Recruitment centers
1
Recruitment center
Name of recruitment center
Clinic of Diet Therapy , Isfahan Clinic Hospital
Full name of responsible person
Hajar Bahador
Street address
Isfahan Hospital ,Ordibehesht Ave SheikhBahaei St
City
Isfahan
Province
Isfehan
Postal code
8183895183
Phone
+98 31 3233 0018
Email
F_taghian@yahoo.com
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Islamic Azad University, Isfahan Branch (Khorasgan), Research Deputy
Full name of responsible person
Majid Toghyani
Street address
Khorasgan University, Arghavanie St, Isfahan
City
Isfahan
Province
Isfehan
Postal code
81551-39998
Phone
+98 31 3500 2352
Email
f_taghian@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Islamic Azad University, Isfahan Branch (Khorasgan), Research Deputy
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic
Person responsible for general inquiries
Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Farzaneh taghian
Position
Associate professor
Latest degree
Specialist
Other areas of specialty/work
Sport Medicine
Street address
NO3, Baharan Ave, Ostad Shahriar St, Robat St
City
Isfahan
Province
Isfehan
Postal code
8183895153
Phone
+98 31335002352
Email
F_taghian@yahoo.com
Person responsible for scientific inquiries
Contact
Name of organization / entity
The University of Khorasgan, Esfahan
Full name of responsible person
Farzaneh taghian
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Sport Medicine
Street address
Khorasgan University, Arghavanie St, Esfahan
City
Isfahan
Province
Isfehan
Postal code
8183895183
Phone
+98 31335002352
Email
F_taghian@yahoo.com
Person responsible for updating data
Contact
Name of organization / entity
Islamic Azad University, Khorasgan branch
Full name of responsible person
Farzaneh taghian
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Sport Medicine
Street address
Khorasgan University , Arghavanie St, Isfahan
City
Isfahan
Province
Isfehan
Postal code
8155139998
Phone
+98 31 3500 2352
Email
F_taghian@yahoo.com
Sharing plan
Deidentified Individual Participant Data Set (IPD)
No - There is not a plan to make this available
Justification/reason for indecision/not sharing IPD