Comparison of the Effectiveness of Kefir and Yogurt on Antropometric and Metabolic Parameters, Vaspin, Metabolic Endotoxemia and Appetite in Patients undertake Bariatric Surgery and follow up of Weight Change, Body Shape Conception, Food Intake and Appetite in Patients after Completing the Intervention Phase

Comparison of the effects of kefir and yogurt on anthropometric parameters, body composition, appetite, lipid profile and blood glucose, serum levels of vaspin and lipopolysaccharide in obese patients undergoing bariatric surgery

This study is a clinical trial with a control group in parallel design and single blind. In each group, 24 patients undergoing bariatric surgery enter the study from day 14 after surgery and consume 100 g of yogurt or kefir daily for 8 weeks. In addition to completing the 8-week intervention phase, all patients will be rechecked for some parameters in the 16th week after surgery.

In this clinical trial study, patients admitted to Ghadir Shiraz Maternal and Child Hospital for bariatric surgery were evaluated for inclusion criteria and enter the study by completing a written consent. Patients will receive 100 grams of yogurt or kefir daily for 8 weeks from day 14 after surgery. At the end, blood sampling, questionnaires, anthropometric measurements, blood pressure, and body composition will be performed. At week 16 after surgery, patients will be assessed for weight, body composition and appetite. Only patients do not know if they receive yogurt or kefir (single blind).

age 20 to 60 years, BMI greater than 40 or more than 35 with comorbidity disease, patient undergoing bariatric surgery; Chronic gastrointestinal and liver disease, Get antibiotics, nosocomial infections, hospitalization for more than 10 days, consumption of probiotic supplements in the past month

In this study, the intervention group will receive kefir and the control group will receive yogurt as placebo for maximum similarity.

Anthropometric parameters; Body composition; Appetite; Lipid profile; Insulin and FBS; vaspin; Serum lipopolysaccharide

Patients included in this study will be unaware that they are in the yogurt recipient group or in the kefir recipient group. On the other hand, due to the similarity of appearance of both products in the packages of similar appearance and with the same label given to the participants, it has been tried to blind the patients. But other people involved in the process know how to classify intervention and control groups.

Informed Consent Form and Clinical Study Report; The informed consent form, based on the frameworks of the research deputy of Shiraz University of Medical Sciences, will be completed by patients before the intervention begins. Clinical study report: Information that is relevant to the main outcome of the study will be shared after non-identifiable information is shared.

Start of access period 8 months after publication of results.

Everyone is allowed to submit a request.

Depending on the circumstances, the time will be decided.

basirat@sums.ac.ir

If the submitted request is responsive after consultation with the research team, the applicant receives the requested documentation within a one-month period.