Protocol summary

Summary
The study goal is comparing the effectiveness of home-based aerobic and resistance exercise training versus supervised aerobic or strength training on physical fitness, weight loss and muscle mass in obese patients after Bariatric surgery. This study includes 90 patients who had Bariatric surgery 6 weeks ago. The evaluation includes medical history and physical examination, measurement of weight and height to calculate body mass index .Then patients will undergo the 6-minute walking test to determine physical fitness. We evaluate fatigue and shortness of breath based on Borg Scale questionnaire and muscle strength by Dynamo meter. Then Patients will be randomized to 3 different groups: Group 1 includes 30 patients who will receive conventional therapy including sessions how to do aerobic and resistance exercise, supplemental handbook as a reminder for exercises they are supposed to do as well as a pedometer to keep track of their physical activity . Group 2 includes 30 patients who will receive conventional therapy plus 2 sessions of strength training per week each for an hour under supervision of a Sports Medicine physician. Group 3 Includes 30 patients who will receive 2 hourly sessions of aerobic exercise per week supervised by a sport medicine specialist in addition to conventional therapy. At the end of the 3 months we will re-measure all parameters and compare them to the initial values to find out if our interventions by using supervised training make a difference between the values of 3 different groups.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT201111064251N6
Registration date: 2011-12-29, 1390/10/08
Registration timing: registered_while_recruiting

Last update:
Update count: 0
Registration date
2011-12-29, 1390/10/08
Registrant information
Name
Haleh Dadgostar
Name of organization / entity
Tehran University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 2200 4050
Email address
halehd@iums.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice chancellor for research of Tehran University of Medical sciences
Expected recruitment start date
2011-08-06, 1390/05/15
Expected recruitment end date
2012-08-05, 1391/05/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of home base exercise versus supervised exercise therapy on weight loss, fitness and muscle mass in patients undergoing Bariatric surgery
Public title
The effect of home base exercise versus supervised exercise therapy on weight loss, fitness and muscle mass in patients undergoing Bariatric surgery
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: patient with Bariatric Surgery in 1-3 months ago. Exclusion criteria: 1. Those with heart disease may include: heart valve disease , ischemic heart disease , uncontrolled symptomatic arrhythmia , hypertrophic cardiomyopathy; 2.Patients with high systolic blood pressure ≥ 200 and high diastolic blood pressure ≥90; 3. Uncontrolled metabolic diseases; 4. Neuromuscular, musculoskeletal and rheumatoid disease that Resonance with exercise; 5. Acute pulmonary embolism; 6. Symptomatic chronic heart failure.
Age
From 15 years old to 65 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 90
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics comitte of Tehran University of Medical Sciences
Street address
Ghods street, Keshavarz Blvd.
City
Tehran
Postal code
Approval date
2011-11-19, 1390/08/28
Ethics committee reference number
130.1764/ص/90

Health conditions studied

1

Description of health condition studied
weight loss in morbid obese patients
ICD-10 code
E66.8
ICD-10 code description
Morbid obesity

Primary outcomes

1

Description
Body mass index
Timepoint
6 weeks after bariatric surgery and 4.5 months after surgery
Method of measurement
BMI = ( Weight in Kilograms / ( Height in Meters x Height in Meters

2

Description
physical fitness
Timepoint
6 weeks after bariatric surgery and 4.5 months after surgery
Method of measurement
6-minute walk test

3

Description
Muscle mass
Timepoint
6 weeks after bariatric surgery and 4.5 months after surgery
Method of measurement
Bioelectrical impedance analysis

4

Description
muscle strength
Timepoint
6 weeks after bariatric surgery and 4.5 months after surgery
Method of measurement
hand daynamo meter

5

Description
Exertional dyspnea
Timepoint
6 weeks after bariatric surgery and 4.5 months after surgery
Method of measurement
Borg scale questionnaire

Secondary outcomes

1

Description
waist circumference
Timepoint
6 weeks after bariatric surgery and 4.5 months after surgery
Method of measurement
in centimeters by Tape

2

Description
Heart rate
Timepoint
6 weeks after bariatric surgery and 4.5 months after surgery
Method of measurement
Stethoscope

3

Description
weight
Timepoint
6 weeks after bariatric surgery and 4.5 months after surgery
Method of measurement
in kilograms by Balance

Intervention groups

1

Description
Group 1: includes 30 patients who will receive conventional therapy including session of how to do aerobic and resistance exercise, supplemental handbook as a reminder for exercises they are supposed to do as well as a pedometer to keep track of their physical activity.
Category
Lifestyle

2

Description
Group 2: includes 30 patients who will receive conventional therapy plus 2 sessions of strength training per week each for an hour under supervision of a Sports Medicine physician
Category
Lifestyle

3

Description
Group 3: Includes 30 patients who will receive 2 hourly sessions of aerobic exercise per week supervised by a sport medicine specialist in addition to conventional therapy.
Category
Lifestyle

Recruitment centers

1

Recruitment center
Name of recruitment center
Obesity clinic of Rasoul Akram Hospital
Full name of responsible person
Hanieh Adib MD
Street address
Rasoul Akram Hospital, Sattar Khan Ave., Niaiesh St.,
City
Tehran

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Vice chancellor for research, Tehran University of Medical Sciences
Full name of responsible person
Akbar Fotouhi MD
Street address
Tehran University of Medical Sciences, Keshavarz Boulvard, Ghods St.
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice chancellor for research, Tehran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Haleh Dadgostar MD
Position
Assistant professor
Other areas of specialty/work
Street address
Rasoole Akram Hospital, Shar_Ara st., Sattarkhan st.
City
Tehran
Postal code
Phone
+98 21 64351
Fax
Email
halehd@iums.ac.ir; hldadgostar@gmail.com
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Haleh Dadgostar MD
Position
Assistant professor
Other areas of specialty/work
Street address
Rasoole Akram Hospital, Shar_Ara st., Sattarkhan st.
City
Tehran
Postal code
Phone
+98 21 64351
Fax
Email
halehd@iums.ac.ir ; hldadgostar@gmail.com
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Hanieh Adib MD
Position
Assistant
Other areas of specialty/work
Street address
Rasoole Akram Hospital, Shar_Ara st., Sattarkhan st.
City
Tehran
Postal code
Phone
+98 21 6435 2156
Fax
Email
hanieadib@gmail.com
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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