Comparison Of The Effect Of Eight Weeks Of Combined Exercise And Curcumin Supplementation On C - Reactive Protein, Ferritin, ESR And Some Functional Factors In Obese Elderly Men
Comparison of eight weeks of combination training and curcumin supplementation and combination of c-reactive protein, ferritin, ESR and some functional factors in obese elderly men
Design
Intervention group 1: Curcumin supplementation The participants in the curcumin supplementation group received 8 mg of curcumin nanomyscle capsule daily for 8 weeks before lunch.Intervention group 2: Combined exercises (resistance and aerobic exercise) for 8 weeks Subjects Relevant activities were performed 3 times (3 sets) 6 days a week and 8 to 10 times for 8 weeks in order.Aerobic training started with 55% of maximal reserve heart rate and increased to 75% of maximal heart rate over 8 weeks. The program started 6 consecutive sessions a week from 30 minutes in the first sessions to 54 minutes in the last sessions.Intervention group 3: The control group was followed up only without intervention
Settings and conduct
Interested individuals were invited to participate in this study by meeting and interviewing in Isfahan Sport Stations. Then, in coordination with the station trainer, a questionnaire was prepared to obtain personal information and medical history and was given to overweight and obese men.
Participants/Inclusion and exclusion criteria
36 elderly men with a BMI greater than or equal to 30 kg as well as inclusion criteria, including those with no specific illness or history of regular physical activity and who did not use special weight loss programs, had biliary problems. They were not prepared and were ready to start physical activity
Intervention groups
Intervention group 1: Curcumin supplementation group
Intervention group 2: Combined exercise group
Intervention group 3: Curcumin supplementation and Combined exercise group
Main outcome variables
Reactive Protein C. Ferritin. ESR
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20170510033909N8
Registration date:2020-04-21, 1399/02/02
Registration timing:retrospective
Last update:2020-04-21, 1399/02/02
Update count:0
Registration date
2020-04-21, 1399/02/02
Registrant information
Name
فرزانه تقیان
Name of organization / entity
دانشگاه آزاد اسلامی.واحد اصفهان
Country
Iran (Islamic Republic of)
Phone
+98 913 308 0241
Email address
f.taghian@khuisf.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2018-12-22, 1397/10/01
Expected recruitment end date
2019-01-20, 1397/10/30
Actual recruitment start date
2018-03-21, 1397/01/01
Actual recruitment end date
2018-04-19, 1397/01/30
Trial completion date
2019-07-21, 1398/04/30
Scientific title
Comparison Of The Effect Of Eight Weeks Of Combined Exercise And Curcumin Supplementation On C - Reactive Protein, Ferritin, ESR And Some Functional Factors In Obese Elderly Men
Public title
The effect of curcumin plus combination exercises on inflammatory and functional factors in obese older men
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Age range of 60 to 75 years
BMI> 30
Exclusion criteria:
No regular physical activity
No biliary disease
No smoking and alcohol
Age
From 60 years old to 75 years old
Gender
Male
Phase
3
Groups that have been masked
No information
Sample size
Target sample size:
45
Actual sample size reached:
36
Randomization (investigator's opinion)
Randomized
Randomization description
Simple randomization , Random number table ،
To use random numbers, the researcher first predefines the reader for reading table numbers (for example, up, down, left, or right), the second is to consider numbers for different groups (for example, pair numbers for intervention A and individual numbers for Intervention B, another way of taking numbers from 2400 to intervene A, and numbers 25-49 for intervention B, are numbers 74-50 for group C and numbers 99-75 for group D), then put on one of the numbers and In one direction, it has been predefined and recorded numbers and allocated to different groups.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics Committee on Research Islamic Azad University Isfahan Branch (Khorasgan)
Street address
Islamic Azad University Isfahan Branch (Khorasgan),Arghvaniyah,Isfahan
City
Isfahan
Province
Isfehan
Postal code
81551-39998
Approval date
2019-07-20, 1398/04/29
Ethics committee reference number
IR.IAU.KHUISF.REC.1398.139
Health conditions studied
1
Description of health condition studied
Elder
ICD-10 code
ICD-10 code description
Primary outcomes
1
Description
Reactive protein C
Timepoint
At the beginning and end of the study after 8 weeks
Method of measurement
Alisa method with RT kit-(State fax 2000)
2
Description
Ferritin
Timepoint
At the beginning and end of the study after 8 weeks
Method of measurement
Alisa method with RT kit-(State fax 2000)
3
Description
ESR
Timepoint
At the beginning and end of the study after 8 weeks
Method of measurement
Alisa method with RT kit-(State fax 2000)
4
Description
Functional
Timepoint
Before and after the last training day
Method of measurement
Based on standard tables
Secondary outcomes
empty
Intervention groups
1
Description
Intervention group: Supplementation of curcumin (Daily intake of an 80 mg nanocrystalline curcumin capsule)
Category
Rehabilitation
2
Description
Intervention group: Combined exercises(Aerobic and official exercises 6 sessions per week) This group was a combination of aerobic and resistance training with Traband.
Category
Treatment - Other
3
Description
Intervention group 3:Curcumin supplementation and combination exercises (three-time exercise) were performed 6 days a week for 24 sessions, and an 80 mg capsule of curcumin nanomixel was taken daily before lunch.
Category
Treatment - Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Isfahan Sports Station No. 33
Full name of responsible person
Niloofar Malekipoor
Street address
Kamal Ismail Park
City
Esfahan
Province
Isfehan
Postal code
8160000001
Phone
+98 31 3431 4480
Email
Niloofarsadr2017@yahoo.com
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Islamic Azad University, Isfahan Branch (Khorasgan), Research Deputy
Full name of responsible person
Majid Toghyani
Street address
Khorasgan University, Arghavanie St, Isfahan
City
Isfahan
Province
Isfehan
Postal code
81551-39998
Phone
+98 31 3500 2352
Email
f_taghian@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Islamic Azad University, Isfahan Branch (Khorasgan), Research Deputy
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic
Person responsible for general inquiries
Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Farzaneh Taghian
Position
PHd,Academic Asistance
Latest degree
Ph.D.
Other areas of specialty/work
Sport Medicine
Street address
Isfahan
City
Isfahan
Province
Isfehan
Postal code
8183895153
Phone
+98 35002352
Fax
Email
F_taghian@yahoo.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Farzaneh Taghian
Position
PHd.Academic Asistance
Latest degree
Ph.D.
Other areas of specialty/work
Sport Medicine
Street address
Isfahan
City
Isfahan
Province
Isfehan
Postal code
81551-39998
Phone
+98 31 3500 2352
Fax
Email
f_taghian@yahoo.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Farzaneh Taghian
Position
PHd.Academic Asistance
Latest degree
Ph.D.
Other areas of specialty/work
Sport Medicine
Street address
Isfahan
City
Isfahan
Province
Isfehan
Postal code
81551-39998
Phone
+98 31 3500 2352
Fax
Email
f_taghian@yahoo.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)
No - There is not a plan to make this available
Justification/reason for indecision/not sharing IPD