Investigating the changes of Tumor necrosis factor-α and Interleukin-10 after 8 weeks of regular Pilates exercise and vitamin D intake in overweight men

Investigating the changes of Tumor necrosis factor-α and Interleukin-10 after 8 weeks of regular Pilates exercise and vitamin D intake in overweight men

The present quasi-experimental study was performed using a pretest-posttest design with control group in a single blind manner. Subjects were randomly divided into four groups: control, Pilates exercise, vitamin D and combination. Pilates and combination training groups perform 8 weeks of Pilates training. Vitamin D and exercise+vitamin D groups will receive 50,000 IU of Vitamin D per week for 8 weeks

The statistical population includes sedentry adult men with overweight (body mass index between 25 and 29 kg / m 2), aged 45-55 years, referred to Ghaemshahr sports clubs. Pilates exercises are performed at 50-70% of heart rate reserve and three sessions per week for 8 weeks at the Paya Sports Club in Ghaemshahr. Subjects in the vitamin D and combination groups, vitamin D and exercise and control groups, will receive placebo in a single blind manner.

Inclusion criteria: Being a non-athlete, being overweight Exclusion criteria: smoking, use of special drugs, use of any supplements

Intervention group 1: This group will do 3 sessions of Pilates training for 3 weeks and take placebo weekly. Intervention group 2: receive 50,000 IU of vitamin D weekly. Intervention group 3: In addition to Pilates exercises, they receive 50,000 IU of vitamin D. Control group: will only take placebo weekly.

25-Hydroxy vitamin D; tumor necrosis factor-alpha; interleukin 10; C reactive protein ; glucose, insulin, insulin resistance, thyroid-stimulating hormone, lipid profile; liver enzymes; renal enzymes, sleep quality

The subjects will be divided into four groups of control, exercise, vitamin D and exercise + vitamin D using simple randomization table. First a number is assigned to each person. Then, using the random number table of each selected number, it is assigned to one of the groups at random and will continue until the number of individuals in each group is completed. Therefore, the researcher will have no option to change or predict the status of individuals. Random concealment will be done by a third person who does not participate in other stages of intervention.

Participants and analysts will be blind. The researcher will administer vitamin D capsules (50,000 units) to vitamin D and exercise + vitamin D individuals as well as placebo to control and exercise groups