The effects of Spirulina Platensis on anemia status in patients with ulcerative colitis

The aim of the study is evaluating the effects of spirulina supplementation on anemia status in patients with ulcerative colitis

Parallel double-blind (both patients and researchers) randomized controlled clinical trial. The third person places the placebo and spirulina into identical and similar capsules and containers and encodes them randomly. A simple randomization method using random number table is used, and each client receives its own number. In this study 80 individuals will participate. The first group of patients will receive Spirulina 1 g daily and the second group will be age- and sex-matched colitis patients who will be selected as controls and receive placebo. All participants will receive two 500 mg capsules daily. Anemia tests are taken from patients before the intervention and at the end of 8 weeks. finally, the result will be studied using SPSS software.

This study will be done in clinic.

Inclusion criteria: Patients included in the study had mild or moderate levels of ulcerative colitis and were between 18 and 65 years of age. Exclusion criteria: Patients with severe ulcerative colitis or other chronic diseases. People during pregnancy or lactation. Smokers or alcohol users. Taking antidepressants and anxiety medications. Taking antioxidant and omega-3 supplements in the last three months.

People with mild or moderate level of ulcerative colitis, ranging in age from 18 to 65 years old will be assigned to receive spirulina supplements (n=40) and placebo (n=40). The group of patients in intervention group will receive Spirulina (Arthrospira platensis) 1 g daily (receive two 500 mg capsules daily) for 8 weeks, and the group of patients in the control group will receive starch 1 g daily (receive two 500 mg capsules daily) for 8 weeks.

anemia status

In the exclusion criteria section, the use of anemia drugs has been added.

In this study, a simple randomization method using random number table is used. This method first uses a random number table, which is a set of numbers that have no pattern or order and which is completely generated. The researcher divides these numbers randomly between the intervention and placebo groups. With the presence of clients, the researcher begins to read the numbers in the specified order. Each client receives its own number and is randomly assigned to either the intervention or the placebo group.

This study is a double-blind study. Given that the researcher and patient should not be aware of the contents of the capsules, the third person places the placebo and spirulina into identical and similar capsules and containers and encodes them randomly. Spirulina and placebo are then presented to the researcher with a code to disclose to the patient.