Effect of 12 weeks combined training (aerobic-resistance) and zataria multiflora supplementation on the levels of some inflammatory adipokines in overweight and obese women

The effect of 12 weeks of combined training (aerobic-resistance) with thyme supplementation on RBP-4, resistin, insulin resistance and body fat percentage in overweight and obese women

This study is a double-blind, factorial randomized clinical trial. The target population of 40 women is overweight and obese. The intervention and control groups receive 500 mg of thyme supplement or placebo daily for 12 weeks. The combined training program is 12 weeks, 3 sessions per week, 30 minutes of aerobic exercise with an intensity of 60 to 70% of the maximum heart rate and 30 minutes of resistance training with an intensity of 10 maximum repetitions.

The placebo and thyme supplement are placed inside the capsule in exactly the same way, participants and researchers will not be aware of the type of supplement received. Exercises are performed in a sports club and blood sampling is performed by a laboratory sampler.

Inclusion: Failure to participate in regular exercise during the last year, no type 2 diabetes, cardiovascular disease and hypertension and systemic and malignant diseases, no consumption of alcohol and drugs or dietary supplements , age range 20-35 Lack of physical restraint in order to participate in sports exercises, signing an informed consent.exclusion: Absence from more than one session in the exercise program, allergy to thyme supplement, forcing to take medication or other nutritional supplements, injury and inability of the subject to continue the exercise program, not participating in one of the blood sampling stages

After filling in the individual consent form, the subjects are randomly divided into four groups of 10 people: placebo, thyme supplement, aerobic exercise, aerobic exercise + thyme supplement.

RBP-4, resistin, body fat percentage and insulin resistance

Using the lottery method, the names of the subjects are written on separate papers and placed in a container, then the names of the subjects are randomly taken out and placed in the intervention group or placebo. The first 30 names in the intervention group and the rest They are in the placebo group.

In order to eliminate the error caused by the participants' and researcher's knowledge of the type of treatment received and its possible effect on the research result, we conduct a two-way study. Due to the fact that thyme supplements are placed exactly the same inside the capsule, participants and researchers are not aware of the type of supplement received.