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Protocol summary

Study aim
the effect of Transdiagnostic Cognitive Behavior therapy on Emotion Regulation, Repetitive Negative Thought, Social Adjusting in Adolescents With Sub-clinical Diagnostic of Emotional Disorders.
Design
A randomized controlled trial will use the Excel software rand function for randomization.
Settings and conduct
The intervention is individual and will be done in 12 sessions online. The length of the sessions will be 45 minutes. The evaluator and therapist of the project will be an individual who will perform the protocol modalities according to the protocol as well as the number of sessions designated for each modal.
Participants/Inclusion and exclusion criteria
Entry criteria: Presence of sub-clinical symptoms, Age range 12 to 17 years, No severe psychiatric disorders, Abstinence from drugs and alcohol in the last three months,Failure to receive cognitive-behavioral interventions, Failure to receive medication, Participants' interest in participating in the research, No chronic medical illness Exist criteria : Receiving other similar psychological interventions, Medication at the same time as the intervention
Intervention groups
12 45-minute treatment sessions will be performed for the members of the intervention group. The main focus of the sessions is on cognitive reconstruction, awareness of bodily senses, awareness of the moment, teaching the concepts of contrasting behavior, and the three components of emotion that include thoughts, bodily senses, and behavior. Members of the control group will also not receive any intervention. They will be evaluated in only three periods.
Main outcome variables
ٍEmotion regulation, Repetitive Negative Thoughts, Social adjustment, Preclinical symptoms of anxiety and depression.

General information

Reason for update
Add two new secondary variables to the Clinical trial
Acronym
IRCT registration information
IRCT registration number: IRCT20210428051113N1
Registration date: 2021-06-14, 1400/03/24
Registration timing: prospective

Last update: 2021-10-23, 1400/08/01
Update count: 1
Registration date
2021-06-14, 1400/03/24
Registrant information
Name
vahideh javadi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 24 3372 5349
Email address
vjavadi76@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2021-06-29, 1400/04/08
Expected recruitment end date
2021-08-30, 1400/06/08
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Efficacy of Transdiagnostic Cognitive Behavior therapy on Emotion Regulation, Repetitive Negative Thought, Social Adjusting in Adolescents With Sub-clinical Diagnostic of Emotional Disorders
Public title
The Effect of Cognitive Behavior therapy on Emotion Control, Repetitive Annoying Thought, Adjusting in Adolescents With Mild to moderate Symptoms of Anxiety and Depression
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Presence of sub-clinical symptoms of anxiety and depression Age range 12 to 17 years Participants' interest in participating in the research on the provisions of written consent
Exclusion criteria:
Existence of drug or alcohol addiction Existence of chronic medical disease Having severe psychiatric disorders(psychotic spectrum, bipolar disorders) Receive medication one month before starting treatment Receive cognitive-behavioral interventions for at least 8 sessions in the last 5 years
Age
From 12 years old to 17 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 40
Randomization (investigator's opinion)
Randomized
Randomization description
Randomization will be done using Excel software. halve the number of participants and enter in tow columns 1 and 2. in the second column, we generate a random number using the Rand function option; then we sort the data by their values(ascending or descending). according to the order of numbers 1 and 2, the samples are randomly assigned to two groups.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Other
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Research Ethics Committee of Zanjan University of Medical Sciences
Street address
Karmandan town, Mahdavi Avenu, Zanjan university and Medical Science
City
Zanjan
Province
Zanjan
Postal code
4513956184
Approval date
2021-05-27, 1400/03/06
Ethics committee reference number
IR.ZUMS.REC.1400.053

Health conditions studied

1

Description of health condition studied
Major depressive disorder, single episode
ICD-10 code
F32
ICD-10 code description
Major depressive disorder, single episode

2

Description of health condition studied
Major depressive disorder, recurrent
ICD-10 code
F33
ICD-10 code description
Major depressive disorder, recurrent

3

Description of health condition studied
Persistent mood [affective] disorders
ICD-10 code
F34
ICD-10 code description
Persistent mood [affective] disorders

4

Description of health condition studied
Social phobias
ICD-10 code
F40.1
ICD-10 code description
Social phobias

5

Description of health condition studied
Panic disorder
ICD-10 code
F41.0
ICD-10 code description
Panic disorder [episodic paroxysmal anxiety] without agoraphobia

6

Description of health condition studied
Generalized anxiety disorder
ICD-10 code
F41.1
ICD-10 code description
Generalized anxiety disorder

7

Description of health condition studied
Other mixed anxiety disorders
ICD-10 code
F41.3
ICD-10 code description
Other mixed anxiety disorders

8

Description of health condition studied
Mixed anxiety and depressive disorder
ICD-10 code
F41.2
ICD-10 code description
Mixed anxiety and depressive disorder

Primary outcomes

1

Description
Sub-clinical symptoms of anxiety and depression mean that the necessary criteria for depressive or anxiety disorders are not met, and only symptoms of anxiety and depression that are in the mild to moderate range.
Timepoint
Measurements will be performed in three periods one period before the start of the intervention, 7 days later and 3 months later.
Method of measurement
For the anxiety and depression variable, the 21 _DASS questionnaire will be used. The subject's score in the range of 14-18 for anxiety and 10 to 20 for depression indicates the presence of sub-clinical symptoms of anxiety and depression.

2

Description
Emotion regulation, which means the ability to reduce, increase or modify emotions.
Timepoint
Measurements will be performed in three periods one period before the start of the intervention, 7 days later and 3 months later.
Method of measurement
The Cognitive Emotion Regulation Questionnaire (CERQ) will be used to measure emotion regulation. This questionnaire has 36 items.

3

Description
Repetitive negative thoughts whose main characteristic is repetitive, annoying and unwanted.
Timepoint
Measurements will be performed in three periods one period before the start of the intervention, 7 days later and 3 months later.
Method of measurement
A negative recurring thoughts questionnaire (RTQ_10) will be used to measure this variable. This questionnaire has 10 items.

4

Description
Social adjustment means the ability to adapt and compromise with oneself, the environment and others.
Timepoint
Measurements will be performed in three periods one period before the start of the intervention, 7 days later and 3 months later.
Method of measurement
The Bell Social Adjustment Questionnaire will be used to measure this variable. This questionnaire has 32 items.

Secondary outcomes

1

Description
Cognitive Flexibility
Timepoint
Before the intervention, 14 days and 3 months after the intervention
Method of measurement
Questionnaire of psychological flexibility or acceptance of action with 7 questions (AAQ) Acceptance and Action Questionnaire

2

Description
Stress Vulnerability
Timepoint
Before the intervention, 14 days and 3 months after the intervention
Method of measurement
7 Stress Questions Out of 21 questions in the Depression, Anxiety and Stress Questionnaire (DASS)

Intervention groups

1

Description
Intervention group: The intervention group will be implemented based on an integrated transdiagnostic treatment protocol for adolescents. This protocol has 8 modals that will be implemented in 12 sessions. Protocol modalities include 1) Motivating and maintaining it 2) Identifying emotions and behaviors 3) Introducing emotion-focused behavioral experiments 4) Awareness of bodily senses 5) Flexibility in thinking 6) Awareness of emotional experiences 7) Facing situational emotions 8) Review skills and progress towards goals and maintain achievements. The main focus of the protocol is on emotion and its three basic components, namely thoughts, body senses and behavior. In the thought component, the focus on teaching mental errors is cognitive reconstruction. In the component of bodily senses, techniques of awareness of bodily senses are performed. In the behavior component, the concepts of driver and contrasting behavior are taught. Finally, situational emotion coping techniques and behavioral experiments will be performed. The modals will run for 8 sessions of 45 minutes for approximately 5 weeks. Depending on the age of the client and his / her understanding of the concepts and problems related to preclinical symptoms of emotional disorder that are unique to each client, these modals will be distributed in the sessions and the participation of parents will be determined if necessary.
Category
Treatment - Other

2

Description
Control group: Members of the control group will be evaluated in three periods without receiving any intervention. During this time, they should not seek psychological treatment or medication for their symptoms. The evaluation period for the members of this group lasted four months according to the quarterly follow-up period.
Category
Treatment - Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Beheshti Hospital
Full name of responsible person
Dr Mohsen Dadashi
Street address
Beheshti Hospitalَ, Ark Town.
City
Zanjan
Province
Zanjan
Postal code
4514147814
Phone
+98 24 3354 4004
Email
beheshti@zums.ac.ir
Web page address
https://beheshti.zums.ac.ir/

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Zanjan University of Medical Sciences
Full name of responsible person
Dr Parviz Ghezelbash
Street address
Zanjan University of Medical Science, Mahdavi Avenue.
City
Zanjan
Province
Zanjan
Postal code
4513956184
Phone
+98 24 3301 8100
Email
zums.ac.ir@riasat
Web page address
https://zums.ac.ir/
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Zanjan University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Zanjan University of Medical Sciences
Full name of responsible person
Dr Mohsen Dadashi
Position
Assistant Professor, Faculty Member
Latest degree
Ph.D.
Other areas of specialty/work
Psychology
Street address
Ark Town, Beheshti Hospital
City
Zanjan
Province
Zanjan
Postal code
1578845136
Phone
+98 24 3354 4001
Email
psy.mohsen@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Dr Elnaz Mousavi
Position
Assistant Professor, Faculty Member
Latest degree
Ph.D.
Other areas of specialty/work
Psychology
Street address
Shahid Arabi St, Yemen St, Chamran Highway.
City
Tehran
Province
Zanjan
Postal code
1985717443
Phone
+98 21 23871
Email
Elnaz48.mousavi@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Zanjan University of Medical Sciences
Full name of responsible person
Dr Mohsen Dadashi
Position
Assistant Professor, Faculty Member
Latest degree
Ph.D.
Other areas of specialty/work
Psychology
Street address
Beheshti Hospital, Ark Town
City
Zanjan
Province
Zanjan
Postal code
1578845136
Phone
+98 24 3354 4001
Email
psy.mohsen@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
No - There is not a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
No - There is not a plan to make this available
Clinical Study Report
No - There is not a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
No - There is not a plan to make this available
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