Evaluation of the effect of lavender (Lavandula angustifolia) oral drops in changing dental anxiety score in patients referred for endodontic treatment

The effect of oral lavender drops on reducing anxiety in patients referred for endodontic treatment

A clinical trial with a control group with parallel double-blind groups on 64 patients. A table of random numbers was used for randomization.

If the patient is accidentally placed in the intervention group, he will receive a disposable plastic cup with a lid, the contents of which are not visible, containing 20 oral drops of lavender extract in 250 ml of water. Patients who are randomly assigned to the control group receive a disposable plastic cup with a lid of the same shape, size, and color that contains 20 drops of water poured into 250 ml of water. Due to the fact that lavender extract has a special smell and aroma, in both groups, we cover the plastic cup lid with lavender extract. After 60 minutes of drinking the solutions, the anxiety questionnaire is completed again by the participants of the two groups.

Inclusion criteria: 1. Patients who need endodontic treatment; Exclusion criteria: 1. Age under 12 years. 2. Not have a healthy mental state. 3. Has used anti-anxiety medications such as benzodiazepines in the past week. 4. A woman who is pregnant. 5. A breastfeeding woman 6. Have a history of contact dermatitis symptoms after consuming lavender essential oil. 7. Have a history of allergies to the main components of lavender extract, including linalool. 8. Patients who are taking coumarin.

The study includes two groups of intervention and control. The intervention group receives the main medicine, which is lavender extract. The control group receives water in a glass with same shape and size.

Patients' anxiety scores are measured by a modified dental anxiety questionnaire before and after taking medication or placebo.

In this study, a simple randomization method using a table of random numbers is used. In this study, which includes 64 samples, the numbers 00 to 64 are assigned to the samples. Then we randomly select a table point in the row direction. We select numbers smaller than the size of the study population. The selected numbers are in fact the individual code of the community that is selected as the sample. We will continue this until the sample size is complete and reaches the number 64.

Study participants are not aware of the contents of the glass and whether it was a medicine or a placebo. Before the clinical caregiver gives the medication and placebo to the participants, another person performs the steps of pouring the drug and the placebo into the glass, and in this way, the clinical caregiver is blinded. Also, the main researcher of the project has no information about contents of each glass and does not know anything about which group receive placebo and which group receive medicine.

Only part of the data, such as the original outcome information, can be shared

The access period will be one year after the results are published

The data will be available only to researchers working in academic and scientific institutions

Can be used in similar clinical designs

Dr. Seyed Hamid Razavian Isfahan School of Dentistry Sofeh St. Contact number 09133314371

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