The comparison of the effect of tetracycline sterile ophthalmic ointment as an adjvant to mechanical debridement and mechanical debridement alone in peri-implantitis treatment

The comparison of the effect of tetracycline sterile ophthalmic ointment as an adjvant to mechanical debridement and mechanical debridement alone in peri-implantitis treatment

A single-blind randomized clinical trial with parallel groups on 32 patients.

In this study, 32 patients with pre-implantitis will be treated topically using tetracycline sterile eye ointment. Patients aged 20 years and older with pre-implantitis and radiographic bone resorption.

Inclusion criteria: Presence of pre-implantitis, no history of pre-implant surgery, gingival margin to more than 6 mm deep envelope, positive bleeding, no antibiotics and mouthwash and periodontal treatment in the last 6 weeks, no anti-use Biotics and mouthwash and periodontal treatment are in the last 6 weeks. Exclusion criteria include pregnancy and breast feeding, use of anticoagulants, allergy to tetracycline sterile eye ointment, underlying disease (diabetes, kidney disorders, etc.) and smoking.

Intervention group: After local anesthesia (Xylocaine Dental (lidocaine HCl)) and isolation and drying of tetracycline ointment (AEROTEX) surfaces by placing a flexible needle (cannula blunt) in the periodontal pouch without trauma or damage to periodontal tissue. (Periodontal cover is not placed.) And then patients will undergo mechanical debridement. Control group: After local anesthesia (Xylocaine Dental (lidocaine HCl)) and isolation and drying, patients will undergo mechanical debridement.

Presence or absence of plaque on tooth and implant surfaces (mesial, distal, buccal and lingual surfaces), The distance between the gingival margin and the depth of the envelope is in millimeters, Presence or absence of bleeding after probing, The distance between the acrylic stent and the depth of the pocket.

Randomization will be using sealed envelopes, of which 32 envelopes will be selected in total and will be divided into two categories of 16, which include groups A and B. At the beginning of the patients' arrival, the secretary of the clinic randomly provides the envelopes to the patients and the patients select them and enter the examination area with the envelopes, and then the dentist will determine the group of patients using the envelopes.

The person evaluates the outcome of patients compared to blind study groups. Patients will be treated by the first and second study supervisors.

Study data is categorized and coded with no identifiable individuals.

Access to study data after publication of the result is available in the journal.

Anyone interested in using the data can access the study data.

Study data can be used for comparison with other results.

Refer to the study's scientific or public accountability person for data.

The request will be sent by email to person responsible for scientific or public inquiries.