Evaluate of the impact Yoga and Pilates Training on Serum Prolactin and Cortisol, Selected Psychological, and Physical Indicators in Female Patients with Multiple Sclerosis

Effects of Yoga vs. Pilates Training on PRL and Cortisol Serum Levels, as well as physical and psychological indicators in females with MS

Study 1: Fifteen participants in this study will be volunteers from the MS Center that will randomly be separated into three groups: yoga group (n=5), Pilates group (n=5), and control group (n=5). The intervention groups will engage in 4-week yoga and Pilates exercises, while the control group will maintain their current lifestyle, without doing any regular physical activity or exercise. Study 2: Forty-eight voluntary (48) patients fulfilling the inclusion criteria mentioned in study one will be randomized the three same groups, Yoga (n=16), Pilates (n =16), and control (n =16) group). .

Participants in this study will be volunteers from the MS Center .The intervention will be for 4 weeks in the first study and 8 weeks in the main study of yoga and Pilates exercises and the control group without exercise.

inclusion criteria: EDSS (0-5.5), BMI (range 20-32), and age (range 18-65) and exclusion criteria: Lack of physical exercise, no relapse of the disease in the previous three months, no pregnancy, no history of cardiovascular, metabolic, emotional, cancer, or orthopedic disorders were among the inclusion requirements. Relapse of illness and failure to function were also grounds for exclusion. For the last three months prior to the start of the study, the participants would not have relapses involving the use of corticosteroid medications or cortisone injections

Three yoga group (n=5), Pilates group (n=5), and control group (n=5) in a pilot study and 48 that will randomize to the three same groups, Yoga (n=16), Pilates (n =16), and control (n =16) group) in the main study.

PRL and cortisol level, QOL, IPAQ, Beck, GHQ12,25ft walking test

participants in this study will be volunteers from the MS Center that will randomly be separated into three groups: yoga group (n=21), Pilates group (n=21), and control group (n=21). The randomization sequence will be generated using a computer-generated list of random numbers to create a series of sequentially numbered envelopes containing equal assignments to Pilates and yoga, and waitlist. Recruited participants will be enrolled and assigned a three-digit number in chronological order by a person not involved in the study. Participants will then be randomized to one of the three groups by blocking the stratified sampling method according to age and EDSS.

There is no plan to publish