Protocol summary

Study aim
The aim of this study was to evaluate the radiographic results of the Vertical Expander Screw method for trans alveolar elevating of maxillary sinus: A Single Arm Trial
Design
This is a non-control, double-blind, randomized, clinical trial on 22 patients. Excel software rand function was used for randomization.
Settings and conduct
In this method, using Bone Management Kit (Microdent® ) and using special screws for bone spreading, we will start to expand the bone to the appropriate height and also a drill with a diameter less than the last drill of the relevant implant system to place the appropriate implant. By performing this step, the sinus membrane will be raised.This study will be performed in the periodontics department of Shahid Beheshti Dental School.
Participants/Inclusion and exclusion criteria
Inclusion criteria: the need to place implants in the posterior areas of the maxilla; Need to treat sinus lift in a closed manner. Exclusion criteria: Patients who smoke, inadequate hygiene and the presence of systemic disease with the use of medications that affect bone metabolism
Intervention groups
Intervention group: In 22 patients, sinus lift is performed by VEST method.
Main outcome variables
Evaluation of marginal bone loss (MBL) 6 months after surgery using parallel periapical radiography

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20190712044177N3
Registration date: 2022-04-12, 1401/01/23
Registration timing: registered_while_recruiting

Last update: 2022-04-12, 1401/01/23
Update count: 0
Registration date
2022-04-12, 1401/01/23
Registrant information
Name
Mahdi Kadkhodazadeh
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 8803 2208
Email address
mahdi.sbmu@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-01-21, 1400/11/01
Expected recruitment end date
2022-08-23, 1401/06/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Radiographic assessment of a conservative approach by using the expander screws for tran-salveolar
Public title
sinus lift
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
21 years of age partial edentulism of the97 posterior maxilla sufficient bone width no maxillary sinus pathologies a minimum of 5-7 residual bone height the O’Leary’s plaque index20% achieving adequate primary stability following implant placement.
Exclusion criteria:
poor oral hygiene or lack of regular maintenance systemic diseases or intake of medications known to affect bone metabolism contraindications for sinus floor elevation the presence of parafunctional habits such as bruxism or clenching Smoking
Age
From 21 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Participant
  • Outcome assessor
  • Data analyser
Sample size
Target sample size: 22
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Participants, health care personnel (physicians, nurses, physiotherapists, etc.) who are responsible for patient care, data collectors, and those who evaluate the outcome are unaware of the surgical procedure used. .
Placebo
Not used
Assignment
Single
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Shahid Beheshti University of Medical Sciences
Street address
Department of Periodontics, School of Dentistry, Shahid Beheshti University of Medical Sciencesو Daneshjoo Blvd, Evin, Shahid Chamran Highway
City
Tehran
Province
Tehran
Postal code
1983963113
Approval date
2022-01-04, 1400/10/14
Ethics committee reference number
IR.SBMU.DRC.REC.1400.090

Health conditions studied

1

Description of health condition studied
Maxillary Sinus Pneumatization
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
Marginal Bone Loss
Timepoint
pre0prative and 6 month later
Method of measurement
Periapical Radiographic Evaluation

2

Description
Endo-sinus Bone Gain
Timepoint
6 month after surgery
Method of measurement
Periapical Radiographic Evaluation

Secondary outcomes

1

Description
Pain
Timepoint
Post-operative and 1 week later
Method of measurement
Visual Analogue scale from 0 to 10

2

Description
post-operative complication
Timepoint
Post-operative and 6 month later
Method of measurement
Number of cases with membrane perforation, Implant failure and Infection by Clinical evaluation

Intervention groups

1

Description
Intervention group: Drilling was performed with a starter 128drill (800 rpm) to 1 mm distance from the maxillary sinus 129floor. Then, the first non-traumatic threaded expander 130(Microdent, Spain) was applied into the prepared osteot- 131omy site (Fig. 1). The expansion was continued superiorly 132to reach the cortical bone and push the sinus floor up with 133dome shaped ends. The desired height for the intended 134implant was achieved by gradually increasing the diameter 135of the expander screws. This process was continued until 136the appropriate osteotomy size was created. The penulti- 137mate drill (corresponding to the drill diameter of the 138selected implant system) was subsequently used to the 139bone level height in order to remove the probably highly 140compressed layer.
Category
Treatment - Surgery

Recruitment centers

1

Recruitment center
Name of recruitment center
Department of Periodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences
Full name of responsible person
Mahdi Kadkhodazadeh
Street address
Daneshjoo Blvd, Evin, Shahid Chamran Highway
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
+98 21 2990 2314
Email
mahdi.sbmu@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Afshin Zarghi‬
Street address
7th Floor, Bldg No.2 SBUMS, Arabi Ave, Daneshjoo Blvd, Velenjak
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
+98 21 2243 9770
Email
Intl_office@sbmu.ac.ir
Web page address
http://en.sbmu.ac.ir/index.jsp?siteid=256&fkeyid=&siteid=24&pageid=13079&siteid=256
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Shahid Beheshti University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Zeinab Zamani
Position
Post-Graduate student
Latest degree
Medical doctor
Other areas of specialty/work
Dentistry
Street address
Velenjak St. , Shahid Chamran Highway, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
2240 3075 – 2217 5350-1
Email
Zeinab_zamani@yahoo.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Mahdi Kadkhodazadeh
Position
Professor
Latest degree
Specialist
Other areas of specialty/work
Dentistry
Street address
Evin
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
+98 21 8803 2208
Fax
Email
Mahdi.sbmu@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Mahdi Kadkhodazadeh
Position
Professor
Latest degree
Specialist
Other areas of specialty/work
Dentistry
Street address
Evin
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
+98 21 8803 2208
Fax
Email
Mahdi.sbmu@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Yes - There is a plan to make this available
Data Dictionary
Yes - There is a plan to make this available
Title and more details about the data/document
All data can share after unidentifiable of patients
When the data will become available and for how long
6 month after results publication
To whom data/document is available
All people
Under which criteria data/document could be used
?/
From where data/document is obtainable
Zeinab_zamani@yahoo.com
What processes are involved for a request to access data/document
Send an email to Corresponding Author
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