Randomization method: Quadruple blocking. Explanation of the method: Each sample is assigned a code and these codes are given to a person other than the researcher without the names of the samples and based on randomly assigned block allocation to the volume of 4 blocks (two assignments to the control group and two Assignment to the test group) - in such a way that the letter A will be considered for the test group and the letter B will be considered for the control group. Possible modes in the four blocks of six modes include AABB, BBAA, ABAB, BABA, ABBA, BAAB, each mode will be written on a card and the cards will be assigned the number one to six, then using the dice of the six modes One may be selected and the selected seniors will be divided into two groups based on that. This process will continue until the sample size is completed. block randomization is performed in practice using SAS statistical software. Concealment is done through the SNOSE (Sequentially Numbered, Opaque, Sealed Envelopes) method: based on the size of the research sample, a number of envelopes with aluminum wrappers (in order not to clarify the contents of the envelopes), are prepared and each of the random sequences created is recorded on a card and the cards are inside. Letter envelopes are placed in order. In order to maintain a random sequence, the envelopes are numbered in the same way on the outer surface. Finally, the letter envelopes are glued and placed in a box, respectively. At the time of registration, based on the order in which eligible participants enter the study, one of the envelopes will be opened in order and the assigned group of that participant will be revealed.