Patients with covid-19 referring to Kausar Hospital are included in the study and then they are divided into two groups A and B using the restricted randomization division method with blocks of six. We give fluoxetine (A) to one group and placebo (B) to the other group. In fact, each block of six includes three A and three B. We give fluoxetine (A) to one group and placebo (B) to the other group. In fact, each block of six includes three A and three B. The number of possible states of blocks of six is 20. Among these 20 blocks of six, according to the sample size, a block of six is randomly selected and based on that, the patients are assigned to two groups.
The randomization method is such that to each of the twenty six possible random blocks we assign a sampling number.
(FFFCCC,FCFFCC,FFCCFC,……….,CCCFFFF)
(F represents the fluoxetine group and C represents the placebo group.)
For example:
FFFCCC=00-04
FCFFCC=05-09
FFCCFC=10-14
…….
CCCFFF=95-99
There are twenty categories and each category contains 5 numbers, which are 5 sampling numbers for each block.
Using the table of random numbers, we choose a two-digit number (from 00 to 99) at random.
Suppose the selected number is 08 (or any number between 05 and 09), so the block of six FCFFCC is selected . Considering the sample size of 60, we select ten two-digit random numbers from the table of random numbers, to which ten blocks of six are assigned. We put these ten blocks one after the other . Gradually, when the patient enters the study, one of the letters F or C is assigned to it, which shows which group the patient is in.