Determining the effect of 10 weeks of weightlifting training with added respiratory dead space volume on angiogenic factors in young weightlifters
Design
Clinical trial with 2 parallel, non-blind, randomized groups of 20 patients
Settings and conduct
The subjects performed their sports activities for 10 weeks in the weightlifting hall under the supervision of experienced performers and trainers, which includes a program of warming up, weightlifting movements and cooling down in the assembly for a maximum of one hour and fifty minutes. Exercises are done three to five days a week. The mask and tube exercise group should use their mask and tube throughout the practice of the main movements, except for warm-up and cooling, to increase the dead breathing space.
Participants/Inclusion and exclusion criteria
Beginner weightlifter with at least six months of experience in weightlifting exercises; Age range 18 to 25 years; Body mass index between 19 and 25; Body fat percentage 12-15%; No history of chronic disease (diabetes, hypertension, chronic lung disease, etc.); No history of smoking for at least the last six months; Without musculoskeletal injury or complication; No use of medications and specific weight loss programs and diets; No use of energizers and anabolic steroids in the last three months
Intervention groups
1- Special weightlifting training (snatch- clean and jerk) with the use of oxygen mask during the training on which the ventilator tube with a diameter of 2.5 cm and a length of 204 cm is closed to provide 1000 ml of dead space. 2- Special weightlifting training (snatch- clean and jerk) without using a mask and tube
Main outcome variables
the level of angiogenic factors; blood lactate level; Blood carbon dioxide partial pressure
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20220626055276N1
Registration date:2022-09-27, 1401/07/05
Registration timing:prospective
Last update:2022-09-27, 1401/07/05
Update count:0
Registration date
2022-09-27, 1401/07/05
Registrant information
Name
Ebrahim Banitalebi
Name of organization / entity
University of Shahrekord
Country
Iran (Islamic Republic of)
Phone
+98 38 3242 0537
Email address
banitalebi@sku.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-10-22, 1401/07/30
Expected recruitment end date
2023-03-20, 1401/12/29
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of 10 weeks of weightlifting training with added respiratory dead space volume on angiogenic factors in young weightlifters
Public title
The Effect of Weightlifting Training with Adding Respiratory Dead Space on angiogenesis
Purpose
Other
Inclusion/Exclusion criteria
Inclusion criteria:
Weightlifter boys 18 to 25 years old
Have a body mass index between 19 to 25 with a body fat percentage of 12 to 15%
Have a history of weightlifting training for at least six months
Exclusion criteria:
History of chronic disease (no diabetes, Blood pressure, chronic lung disease, etc.)
History of smoking for at least the last six months
Musculoskeletal injury or complication
Use of medications and weight loss program or special diet
The use of energizers or anabolic steroids even in therapeutic discussions before starting
Age
From 18 years old to 25 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
20
Randomization (investigator's opinion)
Randomized
Randomization description
First, a list of subjects is prepared according to the inclusion criteria and available sampling, after determining the sample size with G power software, 20 people are selected by simple random method and random digits table. First, each person in the list is given a two-digit code, and then randomly, blindfolded and using a finger, we start from a point in the table of random numbers in the direction of the row or column, and we choose a number that is actually the code of a person from the list. which is chosen as a sample and we place them equally in two groups so that the first code is placed in the first group and the second code is placed in the second group and we continue in the same way until reaching the desired sample size.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Research Ethics committees of Shahrekord University
Street address
Faculty of Literature and Human Sciences, Shahrekord University, Rahbar Boulevard
City
Shahrekord
Province
Chahar-Mahal-va-Bakhtiari
Postal code
۸۸۱۸۶۳۴۱۴۱
Approval date
2022-05-31, 1401/03/10
Ethics committee reference number
IR.SKU.REC.1401.016
Health conditions studied
1
Description of health condition studied
Angiogenesis in male weightlifters
ICD-10 code
ICD-10 code description
Primary outcomes
1
Description
Serum concentration of vascular endothelial growth factor
Timepoint
Before and immediately after the first session - before and immediately after the last session - 48 hours after the last session
Method of measurement
It is done by taking blood and measuring with diagnostic kits. Its unit is pg/ml
2
Description
Serum concentration of Hypoxia-inducible factor
Timepoint
Before and immediately after the first session - before and immediately after the last session - 48 hours after the last session
Method of measurement
It is done by taking blood and measuring with diagnostic kits. Its unit is pg/ml
Secondary outcomes
1
Description
Serum concentration of nitric oxide factor
Timepoint
Before and immediately after the first session - before and immediately after the last session - 48 hours after the last session
Method of measurement
It is done by taking blood and measuring with diagnostic kits. Its unit is µmol/l
2
Description
Serum lactate concentration
Timepoint
Before and immediately after the first session - before and immediately after the last session - 48 hours after the last session
Method of measurement
It is done by taking blood and measuring with diagnostic kits. Its unit is mg/dl
3
Description
Blood carbon dioxide partial pressure
Timepoint
Before and immediately after the first session - before and immediately after the last session - 48 hours after the last session
Method of measurement
It is done by drawing blood with a sterile syringe containing heparin anticoagulant and using an Arterial blood gas measuring device. Its unit is mm[Hg].
4
Description
Blood bicarbonate level
Timepoint
Before and immediately after the first session - before and immediately after the last session - 48 hours after the last session
Method of measurement
It is done by drawing blood with a sterile syringe containing heparin anticoagulant and using an Arterial blood gas measuring device. Its unit is meq/L.
Intervention groups
1
Description
Intervention group: Intervention group: exercise group with mask and tube. Using an oxygen mask with a ventilator tube 2.5 cm in diameter and 204 cm long to provide 1000 ml of dead space is used by this group during weightlifting exercises.
Category
Other
2
Description
Control group: exercise group without mask and tube. This group will do their weightlifting exercises without using masks and tubes.
Category
Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Shahrekord University
Full name of responsible person
Ebrahim Banitalebi
Street address
Faculty of Sport Sciences, Shahrekord University, Rahbar Blvd., Shahrekord
City
Shahrekord
Province
Chahar-Mahal-va-Bakhtiari
Postal code
8818634141
Phone
+98 38 3232 1631
Email
banitalebi@sku.ac.ir
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Research and Technology Vice-Chancellor of Shahrekord University
Full name of responsible person
Ahmad Keyvani
Street address
Research and Technology Vice-Chancellor, Central Library Building, Shahrekord University, Rahbar Blvd., Shahrekord
City
Shahrekord
Province
Chahar-Mahal-va-Bakhtiari
Postal code
8818634141
Phone
+98 38 3232 4435
Email
research@sku.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Research and Technology Vice-Chancellor of Shahrekord University
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic
Person responsible for general inquiries
Contact
Name of organization / entity
The University of Shahrekord
Full name of responsible person
Samira Nasiri
Position
Ph.D. Candidate
Latest degree
Master
Other areas of specialty/work
Exercise physiology
Street address
Unit 2, 5th Floor, Danesh pazhohan building, Daneshjou Blvd
City
Tehran
Province
Tehran
Postal code
1984845497
Phone
+98 21 2243 4457
Email
Sa_nasiri@ymail.com
Person responsible for scientific inquiries
Contact
Name of organization / entity
The University of Shahrekord
Full name of responsible person
Ebrahim Banitalebi
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Exercise Physiology
Street address
Faculty of Sport Sciences, Shahrekord University, Rahbar Blvd., Shahrekord
City
Shahrekord
Province
Chahar-Mahal-va-Bakhtiari
Postal code
8818634141
Phone
+98 38 3232 1631
Email
banitalebi@sku.ac.ir
Person responsible for updating data
Contact
Name of organization / entity
The University of Shahrekord
Full name of responsible person
Samira Nasiri
Position
Ph.D. candidate
Latest degree
Master
Other areas of specialty/work
Exercise physiology
Street address
Unit 2, 5th Floor, Danesh pazhohan building, Daneshjou Blvd
City
Tehran
Province
Tehran
Postal code
1984845497
Phone
+98 21 2243 2257
Email
Sa_nasiri@ymail.com
Sharing plan
Deidentified Individual Participant Data Set (IPD)
No - There is not a plan to make this available
Justification/reason for indecision/not sharing IPD
Each person's data alone is useless.
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Not applicable
Data Dictionary
Not applicable
Title and more details about the data/document
Results for the main outcomes will be shared.
When the data will become available and for how long
6 months after printing the results
To whom data/document is available
Academic researchers
Under which criteria data/document could be used
After access, people only have the right to use the study protocol
From where data/document is obtainable
Samira Nasiri will respond via email. Sa_nasiri@ymail.com
What processes are involved for a request to access data/document
The request will be answered after receiving the request and stating the reasons for needing the data within a maximum period of one month