Protocol summary

Study aim
Determining the effect of lateral position after spinal anesthesia on the need for postoperative narcotics
Design
Clinical trial with intervention and control groups, 69 patients sample size, Trial phase 2-3. Simple randomization will be done as a block randomization method.
Settings and conduct
69 participants with entry conditions, among the candidates for percutaneous nephrolithotomy surgery referred to Shahid Labafinejad Hospital in 2022, were randomly divided into two control and intervention groups.
Participants/Inclusion and exclusion criteria
Inclusion criteria: Age 18 and above; Candidate patients for percutaneous nephrolithotomy surgery; Candidate for spinal anesthesia; Patients with satisfaction to participate in the study Exclusion criteria: History of neurological diseases; diabetes; hypertension; History of drug and alcohol abuse; History of vascular disorders in the lower limbs; History of spine surgery; History of psychiatric diseases and psychological disorders; Patients dissatisfied with participation in the study
Intervention groups
Intervention group: After spinal anesthesia, they undergo percutaneous nephrolithotomy surgery in the lateral position. Control group: After spinal anesthesia, they undergo percutaneous nephrolithotomy in supine position.
Main outcome variables
The amount of narcotic needed after the operation; the first time of narcotic consumption; hemodynamics of the patient

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20221109056450N1
Registration date: 2023-01-19, 1401/10/29
Registration timing: retrospective

Last update: 2023-01-19, 1401/10/29
Update count: 0
Registration date
2023-01-19, 1401/10/29
Registrant information
Name
Alireza Jaffari
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 2360 2280
Email address
alirezajaffari@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-12-20, 1401/09/29
Expected recruitment end date
2023-01-19, 1401/10/29
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of lateral position after spinal anesthesia on the need for postoperative narcotics
Public title
The effect of lateral position after spinal anesthesia on the consumption of narcotic drugs after surgery
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria:
Age 18 and above Candidate patients for percutaneous nephrolithotomy surgery Candidate for spinal anesthesia Patients with satisfaction to participate in the study
Exclusion criteria:
History of neurological diseases, diabetes, hypertension History of drug and alcohol abuse History of vascular disorders in the lower limbs History of spine surgery History of psychiatric diseases and psychological disorders Patients dissatisfied with participation in the study
Age
From 18 years old
Gender
Both
Phase
2-3
Groups that have been masked
No information
Sample size
Target sample size: 69
Randomization (investigator's opinion)
Randomized
Randomization description
Sampling will be done as a block randomization method. So, initially, in the Excel software, there are 6 blocks of 4 as (AA, BB), (BB, AA), (AB, BA), (BA, AB). (AB, AB), (BA, BA) are prepared and then these blocks will be arranged from one to six. A is the confirmation of the treatment or intervention group and B is the confirmation of the control group. Then one of these blocks will be randomly selected and based on the sequence of letters A and B in the selected block, the eligible people will be assigned to the treatment or control groups. The random process of selecting blocks and assigning people to the intervention and control groups will continue until the desired sample size is reached.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Shahid Beheshti University of Medical Sciences
Street address
Tabnak Street.
City
Tehran
Province
Tehran
Postal code
1985717443
Approval date
2019-08-22, 1398/05/31
Ethics committee reference number
IR.SBMU.MSP.REC.1398.431

Health conditions studied

1

Description of health condition studied
Complications of spinal anesthesia
ICD-10 code
T88.59
ICD-10 code description
Other complications of anesthesia.

Primary outcomes

1

Description
Pain level
Timepoint
15, 30, 45, 60, 95, 105 and 120 minutes after the surgery
Method of measurement
Visual analog scale (VAS) (0 None; 1-3 Mild; 4-7 Moderate; 8-10 Severe)

2

Description
The amount of narcotic drug consumption after the surgery
Timepoint
15, 30, 45, 60, 95, 105 and 120 minutes after the surgery
Method of measurement
Patient file

3

Description
The first time of narcotic drug use
Timepoint
After entering recovery and within 120 minutes after the surgery
Method of measurement
Patient file

4

Description
Hemodynamic status of the patient
Timepoint
15, 30, 45, 60, 95, 105 and 120 minutes after the surgery
Method of measurement
Non-invasive monitoring device

Secondary outcomes

1

Description
Nausea and vomiting after the surgery
Timepoint
After entering recovery and within 120 minutes after the surgery
Method of measurement
Patient files

Intervention groups

1

Description
Intervention group: After spinal anesthesia, they undergo percutaneous nephrolithotomy surgery in the lateral position.
Category
Prevention

2

Description
Control group: After spinal anesthesia, they undergo percutaneous nephrolithotomy in supine position.
Category
Prevention

Recruitment centers

1

Recruitment center
Name of recruitment center
Labbafinezhad Hospital
Full name of responsible person
Alireza Jaffari MD
Street address
9th Boostan Street, Pasdaran Street
City
Tehran
Province
Tehran
Postal code
1666663111
Phone
+98 21 23601
Email
alirezajaffari@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Afshin Zarghi MD.
Street address
Shahid Arabi st., Yaman St., Shahid Chamran Expressway
City
Tehran
Province
Tehran
Postal code
1985717443
Phone
+98 21 2243 9781
Email
zarghi@sbmu.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Shahid Beheshti University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Alireza Jaffari MD
Position
Associate professor
Latest degree
Specialist
Other areas of specialty/work
Anesthesiology
Street address
9th Boostan Street, Pasdaran Street
City
Tehran
Province
Tehran
Postal code
1666663111
Phone
+98 21 23601
Email
alirezajaffari@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Alireza Jaffari MD
Position
Associate professor
Latest degree
Specialist
Other areas of specialty/work
Anesthesiology
Street address
9th Boostan Street, Pasdaran Street
City
Tehran
Province
Tehran
Postal code
1666663111
Phone
+98 21 23601
Email
alirezajaffari@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Alireza Jaffari MD
Position
Associate professor
Latest degree
Specialist
Other areas of specialty/work
Anesthesiology
Street address
9th Boostan Street, Pasdaran Street
City
Tehran
Province
Tehran
Postal code
1666663111
Phone
+98 21 23601
Email
alirezajaffari@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
The whole data can be shared after unidentifiable people.
When the data will become available and for how long
Start the access period 6 months after printing the results
To whom data/document is available
Only available to scholars working in academic and academic institutions.
Under which criteria data/document could be used
Employed in research centers
From where data/document is obtainable
Person responsible for scientific inquiries
What processes are involved for a request to access data/document
Send email to person responsible for scientific inquiries (alirezajaffari@gmail.com)
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