View older revisions Content changed at 2024-07-12, 1403/04/22

Protocol summary

Study aim
Effects of one session dry needling on balance dysfunction, plantar flexor and inverter muscles spasticity, active and passive ankle range of motion, and limb motor function in patients with stroke.
Design
The clinical trial includes two intervention and control groups, each with a sample size of 11 people, in a parallel grouping form, in a double-blind manner, and with an accessible and randomized sampling method in the grouping.
Settings and conduct
The field of this study is the treatment (rehabilitation) of stroke patients. Patients are referred to Isfahan Rehabilitation Faculty Research Center by neurologists. Consent forms and questionnaires will be obtained from the patients after necessary briefings are provided on the objectives, implementation method, and confidentiality of the patients' information. Then related evaluations and intervention are done. The intervention includes real and sham dry needling. In this study, the outcome evaluator as well as the participants are blindly unaware of the placement of patients in each of the intervention and sham groups.
Participants/Inclusion and exclusion criteria
Stroke patients with at least six months after their lesion’s onset.
Intervention groups
Intervention group: Patients in the test group will receive one session of dry needling treatment in the flexor and invertor muscles of the foot. Each volunteer undergoes a dry needling treatment session. Control group: The intervention in the control group will include receiving a sham needle session. In this group, the intervention method is exactly the same as the test group, with the difference that the needle will not pierce the skin. For this purpose, special needles are used. These needles have the same tube as standard needles, but the needle is blunt and does not penetrate the skin.
Main outcome variables
Balance dysfunction, spasticity

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20221228056963N1
Registration date: 2023-02-03, 1401/11/14
Registration timing: prospective

Last update: 2024-07-12, 1403/04/22
Update count: 1
Registration date
2023-02-03, 1401/11/14
Registrant information
Name
Seyed Mehdi Okhravi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 31 3669 3089
Email address
okhravimehdi@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2023-02-04, 1401/11/15
Expected recruitment end date
2023-07-06, 1402/04/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effects of one session dry needling on balance dysfunction, plantar flexor and inverter muscles spasticity, ankle active and passive range of motion, and limb motor function in patients with stroke
Public title
Effects of dry needling in patients with stroke
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Having a stroke Age 45 to 75 years Spasticity in the plantar flexor and invertor muscles grade 1 or higher on the MMAS scale Ability to stand independently Not taking anti-spasticity drugs and not injecting Botox in the last six months Not suffering from other neurological diseases Not having any kind of fracture and surgery in the lower limb Absence of contraindications for dry needling treatment
Exclusion criteria:
Presence of fixed deformity in the involved ankle of the patient Reluctance to continue treatment Cases of non-use of dry needling
Age
From 45 years old to 75 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Participant
  • Outcome assessor
  • Data analyser
Sample size
Target sample size: 22
Randomization (investigator's opinion)
Randomized
Randomization description
Randomization will be done using Randomization.com website. In this method, according to the intervention (a) and control (b) groups, a block of 4 is determined. Then each sequence is placed on a registration card and inside an envelope. When each patient enters, one of the envelopes is opened and the group assigned to that participant is determined. In this double-blind study, patients and evaluators are unaware of the type of assigned group. Randomization and intervention will be done by a person who is not involved in the evaluation process of patients and the evaluator is also unaware of the type of intervention.
Blinding (investigator's opinion)
Double blinded
Blinding description
In this study, the outcome evaluator as well as the participants are double-blinded. Since the intervention in the test group is done with real dry needling and in the control group with sham dry needling, the patients will not notice the difference in the appearance of the two types of main dry needling and sham dry needling.
Placebo
Used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Research Ethics Committees of University of Social Wefare and Rehabilitation Sciences
Street address
kodakyar Ave., daneshjo Blvd.,Evin, Tehran
City
Tehran
Province
Tehran
Postal code
1985713834
Approval date
2022-12-20, 1401/09/29
Ethics committee reference number
IR.USWR.REC.1401.189

Health conditions studied

1

Description of health condition studied
Stroke
ICD-10 code
G46
ICD-10 code description
Vascular syndromes of brain in cerebrovascular diseases

Primary outcomes

1

Description
Evaluation of static balance indicators
Timepoint
Before and after intervention - One week later - One month later
Method of measurement
Force plate device

2

Description
Evaluation of spasticity
Timepoint
Before and after intervention - One week later - One month later
Method of measurement
Modified modified Ashworth scale

Secondary outcomes

1

Description
Evaluation of dynamic balance indicators
Timepoint
Before and after of intervention - One week later - One month later
Method of measurement
Time up and go test

2

Description
Evaluation of active and passive range of motion of the ankle
Timepoint
Before and after of intervention - One week later - One month later
Method of measurement
Goniometer

3

Description
Functional evaluation of the lower limb
Timepoint
Before and after of intervention - One week later - One month later
Method of measurement
Brunnstrom scale

Intervention groups

1

Description
Intervention group: Patients in the test group will receive one session of dry needling treatment in the flexor and invertor muscles of the foot (gastrocnemius, soleus and posterior tibialis). Each volunteer undergoes a dry needling treatment session. In this study, a needle with dimensions of 50 x 0.3 mm will be used. The needle will be moved in the muscles in a conical way and for one minute as Fast in-Fast out.
Category
Rehabilitation

2

Description
Control group: The intervention in the control group will include receiving a sham needle session. In this group, the intervention method is exactly the same as the test group, with the difference that the needle will not pierce the skin. For this purpose, special needles are used. These needles have the same tube as standard needles, but the needle is blunt and does not penetrate the skin.
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Musculoskeletal research center
Full name of responsible person
Dr. Ebrahim Sadeghi
Street address
Musculoskeletal Disorders Research Center, School of Rehabilitation, West Entrance Gate of Isfahan University of Medical Sciences, Sofeh Blvd., Isfahan, Iran
City
Isfahan
Province
Isfehan
Postal code
81746-73461
Phone
+98 31 3792 5229
Email
msrc@rehab.mui.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
University of social welfare and rehabilitation sciences
Full name of responsible person
Hamid reza Khankeh
Street address
Second Floor,Farabi Building ,University of Social Welfare and Rehabilitation Sciences, kodakyar Ave., daneshjo Blvd.,Evin, Tehran
City
Tehran
Province
Tehran
Postal code
1985713871
Phone
+98 21 7173 2832
Email
hamid.khankeh@ki.se
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
University of social welfare and rehabilitation sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
University of social welfare and rehabilitation sciences
Full name of responsible person
Seyed Mehdi Okhravi
Position
PhD candidate
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
Physiotherapy department, 5th floor, Farabi building, University of Social Welfare and Rehabilitation Sciences, kodakyar Ave., daneshjo Blvd.,Evin
City
Tehran
Province
Tehran
Postal code
1985713871
Phone
+98 21 7173 2895
Email
okhravimehdi@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
University of social welfare and rehabilitation sciences
Full name of responsible person
Dr. Iraj Abdollahi
Position
Professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiotherapy
Street address
Physiotherapy department, 5th floor, Farabi building, University of Social Welfare and Rehabilitation Sciences, kodakyar Ave., daneshjo Blvd.,Evin
City
Tehran
Province
Tehran
Postal code
1985713871
Phone
+98 21 7173 2895
Email
ir.abdollahi@uswr.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
University of social welfare and rehabilitation sciences
Full name of responsible person
Seyed Mehdi Okhravi
Position
PhD candidate
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
Physiotherapy department, 5th floor, Farabi building, University of Social Welfare and Rehabilitation Sciences, kodakyar Ave., daneshjo Blvd.,Evin
City
Tehran
Province
Tehran
Postal code
1985713871
Phone
+98 21 7173 2895
Email
okhravimehdi@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
No - There is not a plan to make this available
Justification/reason for indecision/not sharing IPD
Currently, no decision has been made for publication.
Study Protocol
No - There is not a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
No - There is not a plan to make this available
Clinical Study Report
No - There is not a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
No - There is not a plan to make this available
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