Evaluating the efficiency of transcranial direct current stimulation on hand motor function in healthy individuals.

Determining the level of hand function in the intervention group (transcranial direct current stimulation) before and after the study. Determining the level of hand function in the control group (sham transcranial direct current stimulation) before and after the study

In this randomized controlled clinical trial study (double-blind), 54 samples of healthy individuals aged 45-20 years will be assigned. The researcher will use the Randomization Allocation Software for randomization.

The volunteers will be assigned to intervention and control groups through given numbers 0001 to 0054. The placement of the electrodes, the intervention time, the session intervals, and the sensation caused by the stimulation, which is in the form of itching or burning in the stimulated area will be the same in the two intervention and control groups. The statistical analyser will be unaware of how the candidates are grouped. (two-way blinded).The study is carried out in the physical medicine and rehabilitation department of the AJA University of Medical Sciences.

Inclusion criteria: Healthy individuals aged 45-20 years who are willing to participate in the study and consent to the study objectives. exclusion criteria: Severe, persistent migraine headaches; chronic skin problems; metal plates on the head; use of stimulators or implants; history of epilepsy or head trauma; not tolerating the adverse effects of tDCS.

The intervention group includes 27 individuals with stimulation protocol (anodal) transcranial stimulation with direct current on the primary non-dominant motor cortex (M1) in 20-minute sessions. The volunteers will participate in 5 consequent sessions in three weekly sessions. In this case, the cathode is placed on the supraorbital area of ​​the opposite side.

hand grip hand dexterity

Eligible candidates to enter the study were assigned by random allocation using block randomization method. The recruited individuals were randomly assigned to one of the two groups of (intervention with tDCS) and a control group (sham tDCS), which will use block randomization with different block sizes. The size of the blocks will be a multiple of 2 and a divisor of 54 (2, 4, and 6). Initially, the block sizes are chosen randomly. Then for each block, different permutations are randomly determined by the Randomization Allocation Software. In each block, the number of people in the groups is equal, and blinding is used to not reveal the permutations in the last people of each block.

A direct current stimulator (Neurostim2., Medina Teb, Iran) was used to deliver anodal tdcs in accordance with the current safety limitations with the same protocol and a stimulation intensity of 1-2 mA based on the volunteers tolerance. The volunteers will be assigned to the intervention and control groups through given numbers 0001 to 0054. Also, the placement of the electrodes, the intervention time, the session intervals, and the sensation caused by the stimulation, which is in the form of itching or burning in the stimulated area (the device will not stimulate muscle twitching), will be the same in the two intervention and control groups. In this study, the person who will perform the statistical analysis will be unaware of how the candidates are grouped. (two-way blinded)