Determining the effect of HIIT and intense resistance training on asprosin and CTRP1 levels in overweight and obese men
Design
The current research will be conducted in the form of a semi-experimental design of three groups (HIIT training group, intense resistance training group and control group) with a pre-test-post-test design. Voluntary sampling method and division into three groups will be randomly assigned, 14 overweight and obese people will be placed in the HIIT group, 14 people will be in the intense resistance training group, and 14 people will be in the control group.
Settings and conduct
The intervention will be for 10 weeks and three sessions per week in experimental groups. Before and after 10 weeks, anthropometric and physiological measurements and blood samples will be taken from the subjects and will be analyzed statistically.
Before starting the main training program, there will be a one-week familiarization period with the exercises.
The location of the study will be one of the sports and fitness clubs in Sabzevar city
Participants/Inclusion and exclusion criteria
Healthy overweight and obese men between the ages of 30 and 50 can participate in the study. Athletes, sick men, and those outside the target age range and body mass index cannot participate in the study.
Intervention groups
1. Intense Interval Training (HIIT) group: This group performs intense interval training
2. Intense resistance training group: This group performs high intensity resistance training
3. The control group in the research goes about their daily life
Main outcome variables
Lose weight
Decrease in body mass index
Hormonal changes associated with obesity
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20230301057578N1
Registration date:2023-03-04, 1401/12/13
Registration timing:retrospective
Last update:2023-03-04, 1401/12/13
Update count:0
Registration date
2023-03-04, 1401/12/13
Registrant information
Name
Mehdi Zarei
Name of organization / entity
The university of Neyshabur
Country
Iran (Islamic Republic of)
Phone
+98 51 4330 5000
Email address
mehdizarei@neyshabur.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-12-30, 1401/10/09
Expected recruitment end date
2023-01-06, 1401/10/16
Actual recruitment start date
2023-01-06, 1401/10/16
Actual recruitment end date
2023-01-09, 1401/10/19
Trial completion date
2023-04-08, 1402/01/19
Scientific title
Effect of HIIT and intense resistance training on asprosin and CTRP1 levels in overweight and obese men
Public title
Effect of interval and intense resistance training on asprosin and CTRP1 levels in overweight and obese men
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria:
Body mass index above 25 kg/m2
Not having a physical injury and orthopedic problem
Not having regular sports activity in the last six months
No smoking and alcohol
Not taking medicine
Absence of cardiovascular diseases, diabetes, hypertension, liver disease, hypothyroidism
Exclusion criteria:
Age
From 30 years old to 50 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
42
Actual sample size reached:
42
Randomization (investigator's opinion)
Randomized
Randomization description
Simple random with code and lottery
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
University of Zabul (Research Ethics Committee)
Street address
Campus address 1: Zabul-km two Banjar road campus address
City
zabol
Province
Sistan-va-Balouchestan
Postal code
9861335856
Approval date
2023-02-24, 1401/12/05
Ethics committee reference number
IR.UOZ.REC.1401.013
Health conditions studied
1
Description of health condition studied
Overweight and obesity
ICD-10 code
ICD-10 code description
Primary outcomes
1
Description
Asprosin
Timepoint
the beginning of the study and 48 hours after the end of the training period (in the fasting state)
Method of measurement
Blood sampling and checking of serum levels. ELISA kit will be used
2
Description
CTRP1
Timepoint
the beginning of the study and 48 hours after the end of the training period (in the fasting state)
Method of measurement
Blood sampling and checking of serum levels. ELISA kit will be used
Secondary outcomes
empty
Intervention groups
1
Description
Intervention group: Intermittent training program for 10 weeks with a frequency of 3 days a week, including 4-8 times of running 20-30 seconds at maximum speed (intensity above 90-85% of the reserve heart rate) and with active rest intervals for 90 seconds (including running In intensity, it will be 40-50% of reserve heart rate. In the first and second weeks, the subjects will have four 20-second repetitions, and in the third and fourth weeks, following the principle of overload, they will do six 25-second attempts with the same rest time between repetitions, and in the fifth to last week, 8 repetitions. They will do 30 seconds with 90 seconds rest between repetitions. The intensity of the exercises will be controlled using a polar heart rate monitor. Before starting the training protocol in each session, subjects will have a 5-minute warm-up program and at the end of each training session, they will have a 5-minute cool-down program.
Category
Rehabilitation
2
Description
Intervention group: Subjects of the resistance training group performed leg press, chest press, back of thigh, front of thigh, forearm, back of arm, rowing and underarm pull-up with intensity of 80-85% of one maximum repetition in a circle 6-8 repetitions and 60 - 30 seconds of rest between each movement and 120 seconds of rest between each round of circles. In the first and second week, the number of three rounds and one round will be added every two weeks until it reaches six rounds in the eighth week. Before starting the training in each session, a warm-up program (10 minutes) and a cooling program (5 minutes) will be done at the end of each session.
Category
Rehabilitation
3
Description
Control group: This group does not do sports. Only basic measurements such as measuring anthropometric characteristics and blood sampling will be done.
Category
Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Behnoud Fitness Sports Club
Full name of responsible person
Abas mohamadi
Street address
Siyadati, Siyadati 1
City
Sabzevar
Province
Razavi Khorasan
Postal code
9616649991
Phone
+98 51 4330 5000
Email
Arashmohamadi231@yahoo.com
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
university of neyshabur
Full name of responsible person
Mehdi zarei
Street address
Adib Blvd.
City
neyshabur
Province
Razavi Khorasan
Postal code
9319774446
Phone
+98 51 4330 5653
Fax
Email
zarei.m8716@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
university of neyshabur
Proportion provided by this source
50
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic
Person responsible for general inquiries
Contact
Name of organization / entity
University of Neyshabur
Full name of responsible person
Mehdi zarei
Position
1. Assistant professor, Department of Physical Education and Sport Sciences
Latest degree
Ph.D.
Other areas of specialty/work
Physiology
Street address
Adib Blvd
City
Neyshabur
Province
Razavi Khorasan
Postal code
9319774446
Phone
+98 51 4330 5653
Email
zarei.m8716@yahoo.com
Person responsible for scientific inquiries
Contact
Name of organization / entity
The University of Neyshabur
Full name of responsible person
Mehdi zarei
Position
Assistant professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiology
Street address
Adib Blvd
City
Neyshabur
Province
Razavi Khorasan
Postal code
9319774446
Phone
+98 51 4330 5653
Email
zarei.m8716@yahoo.com
Person responsible for updating data
Contact
Name of organization / entity
University of Neyshabur
Full name of responsible person
Mehdi zarei
Position
Assistant professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiology
Street address
Adib Blvd
City
Neyshabur
Province
Razavi Khorasan
Postal code
9319774446
Phone
+98 51 4330 5653
Email
zarei.m8716@yahoo.com
Sharing plan
Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available