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Study aim
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Determining the effect of nightshade elimination diet on inflammatory and rheumatological factors of rheumatoid arthritis patients
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Design
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single blind parallel randomized clinical trial
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Settings and conduct
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In this study, people are randomly divided into two intervention and control groups (18 people in each group). Block randomization will be implemented, so that there are 2 blocks in each group (each block contains 9 patients), which are divided based on gender and body mass index. Both groups will receive general dietary recommendations and intervention group also receive nightshade elimination diet for 8 weeks.
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Participants/Inclusion and exclusion criteria
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age over 18 years, definitive diagnosis of the disease by a doctor using the criteria of the American College of Rheumatology (ACR), not taking any nutritional supplements, not having a diet during the study and before sampling,the criteria for not entering the study: others Chronic diseases: allergy, CVD, asthma, cancer, depression, Alzheimer's, psychoactive drugs, simultaneous disorder of RA with other rheumatoid diseases and exclusion criteria: smoking, changing therapeutic drugs, taking nutritional supplements, suffering from any type of disease Other during the study are non-compliance with the study protocol, the occurrence of serious complications during the study.
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Intervention groups
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In order to comply with ethics in the research, both groups of patients will receive an general dietary recommendations for 8 weeks (two months), and patients in the intervention group, in addition to these recommendations, will also receive a nightshade elimination diet. In this way, patients are asked to avoid consuming any nightshade vegetables, including tomatoes, eggplants, potatoes, and peppers in any form
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Main outcome variables
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Anthropometric parameters, demographic information, inflammatory and rheumatological indices, clinical outcomes