Comparison of the efficacy and safety of mesotherapy and meso-needling With HAIRCARE medical device class 3 REVITACARE brand in the treatment of male and female pattern androgenic alopecia: A double blinded controlled randomized clinical trial

Comparison of the efficacy and safety of mesotherapy and mesonidelling With medical device class 3 (HAIRCARE ) REVITACARE brand in the treatment of male and female pattern androgenic alopecia: A double-blind controlled randomized clinical trial

A clinical trial with a control group, with a parallel group, double-blind, randomized phase 3 on 30 patients, which was used for randomization from the table of random numbers.

This study is conducted in Rasul Akram Hospital. 30 patients are randomly placed in two groups A and B. The first group is treated with mesotherapy and the second group is treated with mesonedling. Both groups are treated with medical device class 3 HAIRCARE brand REVITACARE for 6 sessions with 3-week intervals. Patients will be examined with the following methods after completing the treatment. 1. Determining the severity of alopecia based on Ludwig criteria in female pattern or Hamilton criteria in male pattern 2. Imaging and Patient global assessment score The doctor and statistician will be blind،e

Entry criteria: 1- Women and men with hereditary hormonal hair loss 2- 18 years old and above and less than 50 years old, 3- Hamilton score 2 to 5 in men and Ludwig score 1 to 3 in women 4- Full satisfaction of the patient to participate in the plan. Inclusion criteria: 1-Platelet disorders or thrombocytopenia 2-Patients receiving anticoagulant medication 3- Patients with malignancy 4- Receiving chemotherapy in the last 5 years

Patients are randomly divided into 2 groups of 15 people. The first group is treated with mesotherapy and the second group is treated with mesonedling, both groups are treated with HAIRCARE brand REVITACARE for 6 sessions with 3 week intervals.

Determining the severity of alopecia, standard photography score, patient satisfaction score

word correction from "drug" to " medical device class 3"

In this study, simple randomization method will be used. In this way, we will have 2 containers. In one of the containers, there will be 30 numbers from 1 to 30, and in vase number 2, there will be 30 sealed envelopes, in which the desired type of treatment is inserted. The process of randomization will be that first we will choose a number randomly from the first container and we will choose an envelope randomly from the second container and put them in a designed box. The number removed from container #1 will take the treatment that was removed from container #2. We will do this for all 30 numbers. That is, we will have 30 numbers in the desired box, and in front of each number there will be an envelope with treatment inside. In this method, the type of intervention that exists inside each envelope is unclear, which is the randomization concealment method. In fact, the treatment assigned to the numbers is not known until the person comes and the envelope is opened for him, and secondly, the names of the treatments will not be clear inside the envelopes, and the names of the treatments will be A and B, and only the study designer He will know about the type of treatment A and B

The doctor who rates the results of the study and the statistician do not know which treatment group the patient is in.