Protocol summary

Study aim
Investigating the effectiveness of compassion-focused therapy on psychological symptoms of women with recurrent spontaneous abortion
Design
A randomized controlled group with parallel-group, unblinded, on 52 patients. The online Randomly assign tool was used for randomization.
Settings and conduct
Clinical trial with repeated measures, parallel-group, single-blinded, randomized on 52 patients, random list generator app used for randomization
Participants/Inclusion and exclusion criteria
Age above 18؛ History of recurrent spontaneous abortion (having at least 2 miscarriages)؛ Not participating in psychological interventions during the last year؛ In case of taking psychiatric drugs, no change in the drugs during the last 6 months.
Intervention groups
In group one participants will undergo ten 60-minute psychotherapy sessions utilizing a compassion-focused treatment approach. The group two will consist of participants on a waiting list, who will not receive any intervention until the end of the first group's sessions.
Main outcome variables
Depression score؛ Anxiety score؛ Resilience score؛ Body image concern score؛ Internalized shame score؛ Perinatal grief score

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20230924059503N1
Registration date: 2023-11-29, 1402/09/08
Registration timing: retrospective

Last update: 2023-11-29, 1402/09/08
Update count: 0
Registration date
2023-11-29, 1402/09/08
Registrant information
Name
Mohammadreza Norouzi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 2243 9770
Email address
mnorouzi@sbmu.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2023-09-26, 1402/07/04
Expected recruitment end date
2023-10-26, 1402/08/04
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effectiveness of compassion-focused therapy on psychological symptoms of women with recurrent spontaneous abortion
Public title
compassion-focused therapy for women with recurrent spontaneous abortion
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
age above 18 History of recurrent spontaneous abortion (having at least 2 miscarriages)
Exclusion criteria:
participating in psychological interventions during the last year In case of taking psychiatric drugs, change in the drugs during the last 6 months
Age
From 18 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 52
Randomization (investigator's opinion)
Randomized
Randomization description
All the people who entered the study were given a code, then these codes were entered into the Randomly assign online software (https://www.graphpad.com/quickcalcs/randomize1.cfm) and the software randomly assigned each code to a group.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committe of Shahid Beheshti University of Medical Science
Street address
Bldg No.2 Shahid Beheshti University of Medical science, Arabi Ave, Daneshjoo Blvd, Velenjak, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1983963113
Approval date
2023-08-29, 1402/06/07
Ethics committee reference number
IR.SBMU.MSP.REC.1402.288

Health conditions studied

1

Description of health condition studied
recurrent pregnancy loss
ICD-10 code
N96
ICD-10 code description
Recurrent pregnancy loss

Primary outcomes

1

Description
Depression score
Timepoint
before treatment, after the treatment, and 6 month after treatment
Method of measurement
Beck depression inventory

2

Description
Anxiety score
Timepoint
before treatment, after the treatment, and 6 month after treatment
Method of measurement
Beck anxiety inventory

3

Description
Resilience score
Timepoint
before treatment, after the treatment, and 6 month after treatment
Method of measurement
Connor-Davidson Resilience Scale

4

Description
Body image concern score
Timepoint
before treatment, after the treatment, and 6 month after treatment
Method of measurement
The Body Image Concern Inventory

5

Description
Internalized shame score
Timepoint
before treatment, after the treatment, and 6 month after treatment
Method of measurement
Internalized Shame Scale

6

Description
Perinatal grief score
Timepoint
before treatment, after the treatment, and 6 month after treatment
Method of measurement
Perinatal Grief Scale

Secondary outcomes

empty

Intervention groups

1

Description
This group underwent ten 60-minute weekly sessions of compassion-focused psychotherapy, aimed at developing a positive therapeutic relationship that facilitates the process of engaging with one's challenges and development of skills to deal with them, developing non-blaming compassionate understandings into the nature of suffering, developing the ability to experience and cultivate compassionate attributes and developing the feeling of compassion for others, being open to compassion from others, and developing self-compassion.
Category
Treatment - Other

2

Description
Control group: This was a waiting list, and clients in this group did not receive any therapy until the end of the therapy of the intervention group.
Category
Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Ayatollah Taleghani Hospital
Full name of responsible person
Mohammadreza Norouzi
Street address
Ayatollah Taleghani Hospital, Arabi Ave, Daneshjoo Blvd, Velenjak, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1985711151
Phone
+98 21 2303 1111
Email
taleghanihospital@sbmu.ac.ir
Web page address

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
‪Dr Afshin Zarghi
Street address
No.2 Shahid Beheshti University of Medical science, Arabi Ave, Daneshjoo Blvd, Velenjak, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
+98 21 2243 9770
Email
Intl_office@sbmu.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Shahid Beheshti University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
mohammadreza Norouzi
Position
PhD candidate
Latest degree
Master
Other areas of specialty/work
Psychology
Street address
No.2 Shahid Beheshti University of Medical science, Arabi Ave, Daneshjoo Blvd, Velenjak, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
+98 21 2243 9770
Email
mnorouzi@sbmu.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Mohammadreza Norouzi
Position
PhD Candidate
Latest degree
Master
Other areas of specialty/work
Psychology
Street address
No.2 Shahid Beheshti University of Medical science, Arabi Ave, Daneshjoo Blvd, Velenjak, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
+98 21 2243 9770
Fax
Email
mnorouzi@sbmu.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
Shahid Beheshti University of Medical Sciences
Full name of responsible person
Mohammadreza Norouzi
Position
PhD Candidate
Latest degree
Master
Other areas of specialty/work
Psychology
Street address
No.2 Shahid Beheshti University of Medical science, Arabi Ave, Daneshjoo Blvd, Velenjak, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1983963113
Phone
+98 21 2243 9770
Fax
Email
mnorouzi@sbmu.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
No - There is not a plan to make this available
Justification/reason for indecision/not sharing IPD
There is no further information
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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