Comparing the effects of bupivacaine and bupivacaine-methylprednisolone in ultrasound guided erector spinae plane block on postoerative pain in Lumbar spine surgery

Comparing the effects of bupivacaine and bupivacaine-methylprednisolone in ultrasound guided erector spinae plane block on post operative pain in Lumbar spine surgery

Clinical trial with control and intervention group, single blind, on 64 patients, randomized with sealed envelope.

Patients referred to Luqman Hospital are divided into two intervention and control groups of 32 people by block randomization. After anesthesia with the same method, both groups will be placed in the prone position before the surgery under ultrasound guidance under bilateral erector spina block at the level of the surgical site. Paramedian sagittal ultrasound probe, about 2 cm outside the spinous processes, we find the transverse process on the same side. We insert the needle caudal to the cranial so that the tip of the needle hits the transverse process. If the needle site is suitable, 20 cc of bupivacaine-methylprednisolone will be injected in the intervention group and 20 cc of bupivacaine 0.25% in the control group. Isoflurane and opioid consumption during surgery, pain, nausea and vomiting during recovery and sugar measurement The blood will be determined up to 24 hours later, as well as the pain level of the patient up to one month.

Inclusion criteria : Patients 18-65 years old; Normal kidney and liver function; ASA score 1-2; Patient consent ; No history of allergies to local anesthetics; No drug addiction Exclusion criteria:, Increase the scope of surgery to more than three level ,time of surgery for more than 6 hours; No diabetes

The intervention group, after anesthesia and changing to the prone position, ,are subjected to erector spinae block with bupivacaine-methylprednisolone, and the control group are subjected to block with bupivacaine

Consumption of isofluran , opioids, pain score

Permuted Randomized Blocks :In this method, 10 random blocks are generated by computer. Each block includes 5 people in the intervention group and 5 people in the control group. The order of these people is randomly arranged by computer and people are assigned to groups in the same way. At the end of each block, a new block of 10 is produced and this process will continue until the final sample volume is reached.

Participants in the study are unaware of the groupings because the intervention is performed after anesthesia. The patient's clinical caregiver, the evaluator and recorder of the results, and the data analyzer are not aware of the grouping.