The effectiveness of Transcranial Direct Current Stimulation (tDCS) on the reading skills of children with dyslexia

Evaluating the effectiveness of tDCS on word, non-word reading, irregular words skills, and reading errors in Persian text in children with dyslexia.

A concealed, randomized, blinded, sham-active clinical trial with a parallel-group design of 28 patients, will enroll between April 2020 and Agust 2021 and follow for one month.

Intervention in this study in a clinic of education in Baharestan (Tehran province) by a therapist for 12 sessions. Both participants and the therapist are blind to whether the participant is in the sham or intervention group.

Have normal IQ (between 85 and 110). Being right-handed. Absence of other psychiatric disorders Utilizing Persian as the mother tongue (Persian native speakers) Absence of sensory-motor disorders Absence of epilepsy Filling out the informed consent form by the parent

For active stimulation the direct current will also be transferred using a saline-soaked pair of surface sponge electrodes (thickness = 0.3 cm; square meters = 25 cm2), which are fixed by a headband. Stimulation will be deliver over the tempo-parietal region (Anodal electrode over the midway between P7 and TP7; cathodal electrode over the midway between P8 and TP8). We apply current at a density of 0.057 mA/cm2. For sham stimulation, the same montage will use. However, the current was ramped up for 30 second and then ramped down.

Non-word reading, irregular word reading, reading errors (misreading, substitution, elimination, addition)

Participants will be randomly assigned to the active and sham groups. A computer-based randomization approach will be used (www.sealedenvelope.com). We will include 40 participants and five blocks of the same size to create a random archive. For concealment in the randomization process, a unique code will be provided to each participant that generate by the software. These codes randomly associate with the cubes that represente the intervention groups. Since the study was double-blind, none of the participants or therapists were informed which group (active or sham) each participant was assigned to.

In this study undermentioned persons will be blind: Evaluator relative to pre and post-intervention assessments - Therapist relative to Sham-active intervention execution (Sham: The placebo state in which the device electrodes are placed on the scalp to create a placebo effect, but no current is sent to the brain. Active: Active stimulation mode (positively charged) where the electrodes are on the scalp and a current of 1 mili Amper (mA) is directed to the brain for 20 minutes, Participants relative to receiving Sham-active intervention execution

The participant data file is confidential and only general information will be entered in the artic