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Study aim
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Using a completely herbal mouthwash with anti-fungal and anti-inflammatory properties..., with less side effects for patients with denture stomatitis
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Design
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Clinical trial with two control and intervention groups, three blind strains, randomized by Balance block randomization , phase 2 on 48 patients
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Settings and conduct
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DS patients referred to Qazvin univercity
Patients are entered into the study with personal consent, then the information related to age, gender, duration of denture use, daily number of mouth and denture cleaning cases, as well as burning sensation and pain in the area are recorded. The dimensions of the erythema in time Entry is measured in mm. Patients are randomly divided into control and intervention groups. In the intervention group, herbal mouthwash is given to the patient and in the control group, nystatin (both mouthwashes are in the same bottles)to gargle 3 times a day for 3-5 minutes for 14 days, one cup each time. Also, in both groups, people were taught to clean their dentures daily .On the 1st, 7th and 14th days, the samples are examined in terms of the size of the existing lesions and the degree of pain and burning sensation.ahso, on the 7th and 14th days, the patient is also asked about the satisfaction with the taste of the medicine.
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Participants/Inclusion and exclusion criteria
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Inclusion:
People who volunteer to participate in the study.
Patients with Denture Stomatitis lesions in the active phase
ٍExclusion:
Improper prosthesis
Suffering from systemic and autoimmune diseases such as diabetes, blood pressure, etc.
The patients' use of any type of medicine that affects the quality and quantity of saliva
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Intervention groups
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Control: Nystatin
intervention: herbal mouthwash
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Main outcome variables
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The size of the lesion, the amount of pain and burning sensation in the mouth, and the satisfaction with the taste of the medicine