Investigating the effect of aerobic exercises along with chest physiotherapy in quality of life of cystic fibrosis patients referred to Masih Daneshvari Hospital.

Investigating the effect of aerobic exercises along with chest physiotherapy in improving the quality of life of cystic fibrosis patients referred to Masih Daneshvari Hospital.

A controlled, parallel-group, double-blind, randomized clinical trial on 40 patients. A table of random numbers was used for randomization.

This study is conducted as a clinical trial on COPD patients referred to Masih Deneshvari Hospital in Tehran. Patients who meet the study entry criteria are placed in one of the two study groups after providing explanations and signing a written consent form.

Inclusion criteria will include age over 18, patients in stable phase, and doctor's definite diagnosis of CF. Also, patients who have contraindications for rehabilitation and respiratory physiotherapy, such as respiratory distress and hemoptysis, or who do not wish to continue participating in the research plan, will be excluded from the study.

In the intervention group, patients will receive common respiratory physiotherapy treatment, including sputum and secretion drainage techniques, breathing exercises. In addition, aerobic exercises using bicycles and treadmills, including 10 minutes of bicycle use as warm up and 15 minutes of walking on the treadmill, the intensity of which is calculated based on the six-minute walking test distance for each person. In the control group, the patients will only receive the common treatment of respiratory physiotherapy, including phlegm and secretion drainage techniques, breathing exercises.

Maximum exercise capacity, FEV1, FVC, RV, TLC, VO2max, fatigue during activity, resting heart rate, oxygen saturation at rest

Randomization method: simple, randomization unit: individual, randomization tool: random number table. To create a random sequence, with the help of a random number table and by a statistical consultant, the patients were randomly given one of the even and odd codes. Patients who were assigned even numbers were in the first group and patients with odd codes were in the second group.

To avoid possible risks, the main researcher is fully aware of the allocation of groups. The person assessing the outcome and analyzing the data is kept blind.