Comparison of the effectiveness of combined treatment of topical l-carnitine 1% and clotrimazole 2% with clotrimazole 2% alone, in patients with scalp seborrheic dermatitis

Determining the effectiveness of the combination treatment of topical l-carnitine lotion 1% along with clotrimazole 2% lotion and clotrimazole 2% lotion alone in the treatment of seborrheic dermatitis of the head

Clinical trial with a control group, with parallel groups, 3 blind strains, randomized, phase 2 on 64 patients, a sealed envelope was used for randomization.

Patients referred to Al-Zahra hospital clinic with seborrheic dermatitis are divided into 2 groups, one group is treated with combination al-carnitine and clotrimazole and the other group is treated with clotrimazole. The patient, the clinical caregiver and the researcher are not aware of the type of treatment. The clinical pharmacist is responsible for the preparation of these materials during the type of groups

Inclusion criteria: suffering from seborrheic dermatitis in the scalp area with clinical diagnosis, no treatment with topical or systemic corticosteroids since four weeks ago, no treatment with methyldopa, chlorpromazine, topical or systemic anti-acne drugs since one month ago, and no systemic disease such as Parkinson's, AIDS and mood disorders Exclusion criteria: history of any drug allergy, lack of consent to participate in the study, failure to visit for follow-up, pregnancy and breastfeeding

The group treated with a combination of 1% L-carnitine topical lotion and 2% Clotrimazole lotion. The group treated with 2% clotrimazole lotion alone

Scalp erythema, peeling, itching; Patient satisfaction

Randomization is done in a simple and individual way using a sealed envelope, so that an envelope is randomly removed for each patient, which contains either L-carnitine and clotrimazole treatment group or clotrimazole alone, which is also is a and b.

The only clinical pharmacist is responsible for the preparation of these substances in the current type of groups, the substances are in tubes of the same shape, only the writing is a or b. The appearance of the tubes is also similar.

All data included demographic variables and potential pre- and post-treatment variables after de-identifying shareable subjects.

Immediately after publication of literature

Only researchers working in academic and scientific institutions

The data is accessible only for further understanding

It should be requested to the responsible author via email

In order to receive the data, it must be done through the university email, after approval by the responsible author, it will be sent within a week