The effects of transcranial alternative current stimulation on pain, central sensitization and functional disability in individuals with chronic low back pain: double-blind randomized clinical trial

The effects of transcranial alternative current stimulation on pain, central sensitization and functional disability in individuals with chronic low back pain: double-blind randomized clinical trial

Clinical trial, factorial, double-blind, randomized, 3 phase on 54 patient. For randomization random allocation software was used.

In this study, the intensity of pain and the level of sensitivity of people to pressure stimuli, the sequence of muscle activation during rapid shoulder flexion will be measured before the study, immediately after and 4 weeks after the end of the treatment. This study will be conducted in the Science and Research Center of Shiraz Rehabilitation Faculty located in Chamran Hospital. The study is double-blind and the evaluator (researcher), clinical caregiver (project partner) and participants will be unaware of how the study was conducted.

age between 18-65, having low back pain for at least three months ago, pain intensity more than equal to 3 in the last week; radicular pain in legs, symptoms of serious underlying conditions such as tumor, infection, vertebral compression fracture, ankylosing spondylitis or spinal stenosis, pregnancy, any contraindication use of transcranial alternative current stimulation

the routine physical therapy treatment group (transcutaneous electrical nerve stimulation, Hot pack, Ultrasound, Exercise), the transcranial alternating current stimulation treatment group, the routine physical therapy and transcranial alternating current stimulation treatment group

pressure pain threshold, temporal summation of pain, conditioned pain modulation, delayed onset of muscle activity, recruitment of muscle activity

Allocation of people to three groups of random samples taken from patients is done completely randomly. Randomization is done based on the random allocation software in a block method with the size of each block being 6. To implement random allocation concealment, non-transparent envelopes sealed with random sequence will be used so that the allocated group is not known before individual allocation. In this method, after generating a random sequence using the block method, based on the specified sample size, a number of envelopes with non-transparent cover are prepared (in order to make the content of the envelopes unclear) and each of the generated random sequences is recorded on a card and the cards are placed in the letter envelopes in order. In order to maintain the random sequence, the outer surface of the envelopes is numbered in the same order. Finally, the lids of the envelopes are glued and placed in a box. At the time of registration of eligible participants for the study, one of the envelopes will be opened and the assigned group of that participant will be revealed.

In this study, the participants are unaware of the allocation of people to different treatment groups, and the clinical caregiver who will be the student's colleague in this study will be unaware of the evaluation method and the outcomes to be evaluated. The outcome assessor, who is the main researcher or student in this study, will be completely unaware of the type of group to which each participant has been assigned.