Assessment of the effect of the combined herbal mouthwash (containing Thymus, Myrtus, Glycyrrhiza and Aloe Vera) and Chlorhexidine (0.2%) on salivary pH and flow rate

Determining the effect of two combined herbal mouthwashes (containing Thymus, Myrtus, Glycyrrhiza and Aloe Vera) and chlorhexidine 0.2% on saliva pH

20 students enter the study. While fasting for 90 minutes, on the first day, unstimulated saliva is collected by spitting, then 20 ml of orange juice is swirled in the mouth for 1 minute and saliva is collected again. In the next step, they are divided into two equal groups, and group A is given a combined herbal mouthwash, and group B is given chlorhexidine mouthwash for 1 minute, and saliva is collected in the above-mentioned manner, and at the end of the first day, the pH of these samples is measured and will be recorded . After 72 hours of washing out, these steps are repeated again, with the difference that the type of mouthwash of the two groups is changed and the pH of the collected saliva samples is measured again. A phase 0 study is considered a trial

In Qazvin Dental Faculty, measuring the pH of saliva samples with a pH meter, double blinding

Qazvin dental faculty students Student willingness and satisfaction to participate in the study Not suffering from any systemic diseases that affect saliva such as diabetes and thyroid diseases - Not using drugs, smoking, alcohol and drugs - Not using anticholinergic drugs, antihypertensives, antidepressants, etc. - Not having a history of radiotherapy; Not using intra-oral devices such as placardodontics Exclusion criteria : lack of satisfaction and lack of proper cooperation of the student

Two groups of 10 people who receive combined herbal mouthwash and chlorhexidine mouthwash and the type of mouthwash is changed in a cross-over manner.

sex Age Type of mouthwash Saliva pH

Patients are assigned to two treatment groups, B and A, using the method of random blocks (balance block randomization). The size of each block is 10 and the total number of blocks is 2. Balanced randomization allocation method for the participants in the randomized crossover clinical trial study in the first group (A) the effect of using 0.2% chlorhexidine mouthwash after one minute and after 20 minutes on saliva pH and in the second group (B) the effect of using The combined herbal mouthwash is checked after one minute and after 20 minutes on saliva pH

When the participants receive the mouthwashes, they do not know the type of mouthwash received, the data analyst also only knows after receiving the data that two types of mouthwashes are being compared and is unaware of their contents.