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Study aim
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Determining the effect of the method of transamic acid use and position on cesarean section bleeding rate, surgical team satisfaction and postoperative complications.
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Design
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Clinical trial with control group, randomized, phase 3 on 102 patients. Blocking was used for randomization
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Settings and conduct
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Intervention group A is the injection of transzymic acid, which in cesarean surgery, after the birth of the baby and the removal of the placenta, one gram of transzymic acid will be injected intravenously.Intervention group B, application of reverse Trendelenberg position with 10 degrees and left tilt position with 15 degrees) after general anesthesia (before the birth of the baby), the bed position will be changed to reverse Trendelenberg position with 10 degrees.Group C: the group without routine intervention.
This study will be conducted in Shahada Kargar Hospital in Yazd in 1403.
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Participants/Inclusion and exclusion criteria
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Inclusion criteria include:
Term women who are candidates for cesarean surgery, not suffering from coagulation and bleeding disorders, not suffering from liver and kidney diseases, no history of thromboembolism, history of singletons, no history of polyhydramnios, oligohydramnios (hemoglobin level 10-15 mg/d and platelets <100 thousand)
Exclusion criteria include:Diagnosis of placental abruption, placental abruption, placenta accreta, uterine atony, intra-abdominal adhesions during operation, bladder, bowel and other internal organs damage during operation, uterine incision expansion and spinal anesthesia during operations.
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Intervention groups
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Group A: injection of transamic acid drug, group B: application of positions (inverted Trendelenberg position 10 degrees and left tilt position 15 degrees) and group C: group without intervention
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Main outcome variables
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Cesarean section bleeding - satisfaction of the surgical team - shoulder pain