Protocol summary

Study aim
Determining and comparing the analgesic effect of erector spina block (ESP) and tap block (TAP) in pain after open inguinal hernia surgery.
Design
Clinical trial with parallel groups, three blind, randomized, on 28 patients. A lottery method will be used to assign patients to the first and second intervention groups.
Settings and conduct
The current study is a three-blind clinical trial study (patients will not be informed about the type and type of nerve block for pain control. The doctor evaluating pain and other variables will be unaware of each patient's group. The data analyst will be from the groups The intervention of uninformed patients will be done in 1403 in the city of Qom and in Shahid Beheshti Hospital, by a surgeon who will undergo hernia surgery.
Participants/Inclusion and exclusion criteria
Entry criteria: Those who were candidates for inguinal hernia repair surgery. Being between 20 and 65 years old. Exclusion criteria: pregnancy, history of drug sensitivity, history of chronic pain syndromes and use of painkillers, alcohol and drug addiction.
Intervention groups
After the end of the surgery and before closing the wound in the first group, they will be nerve blocked by Erector Spina Plana Block method and the second group will be nerve blocked by TAP BLOCK method.
Main outcome variables
Pain reduction / faster treatment / cost reduction

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20240528061926N1
Registration date: 2024-08-11, 1403/05/21
Registration timing: retrospective

Last update: 2024-08-11, 1403/05/21
Update count: 0
Registration date
2024-08-11, 1403/05/21
Registrant information
Name
Morteza Mohaddes
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 25 3616 2651
Email address
drmorteza.mohades@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2024-07-10, 1403/04/20
Expected recruitment end date
2024-08-10, 1403/05/20
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
A comparative study of the analgesic effect of erector spina block and tap block in pain after open inguinal hernia surgery
Public title
A comparative study of the analgesic effect of erector spina block and tap block in pain after open inguinal hernia surgery
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Those who were candidates for inguinal hernia repair surgery. Being between 20 and 65 years old.
Exclusion criteria:
Pregnancy, history of drug sensitivity, history of chronic pain syndromes and use of painkillers, alcohol and drug addiction.
Age
From 20 years old to 60 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Participant
  • Care provider
  • Data analyser
Sample size
Target sample size: 28
Randomization (investigator's opinion)
Randomized
Randomization description
A lottery method will be used to assign patients to the first and second intervention groups. In the first stage, groups are written in the form of group A, B. Then a lottery is drawn between the two groups to determine which intervention group will be the first and which intervention group will be the second. In the second step, the numbers of two cards written on one A and the other B and completely closed and not visible are thrown into a container. Then, after obtaining consent from the patients and agreeing to participate in the study, they are asked to choose one of the two cards in the container in order to determine the intervention group. Then he takes a card from inside the container and hands it to the nurse. The nurse writes down the intervention group and the type of nerve block of the patient according to the group he belongs to, once before the start of the surgery and once again at the start of the nerve block (after the end surgery and before closing the wound) is informed to the attending physician and is performed according to the assigned group. Because the patients are not included in the study at the same time, until the sample size of both groups is completed, the patients will be included in the study one by one after referring for surgery, according to the inclusion criteria.
Blinding (investigator's opinion)
Triple blinded
Blinding description
Patients will not be informed about the method and type of pain control nerve block. The physician evaluating pain and other variables will be unaware of each patient's group. The expert analyzing the data will be unaware of the intervention groups of the patients.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Qom Medical Sciences
Street address
Qom Medical Sciences Research Assistant Building Safashehr St. Qom
City
qom
Province
Ghoum
Postal code
3713649373
Approval date
2023-09-11, 1402/06/20
Ethics committee reference number
IR.MUQ.REC.1402.152

Health conditions studied

1

Description of health condition studied
inguinal hernia
ICD-10 code
K40.0
ICD-10 code description
Bilateral inguinal hernia, with obstruction, without gangrene

Primary outcomes

1

Description
pain relief
Timepoint
Immediately, 6, 12 and 24 hours after surgery
Method of measurement
Visual ruler of pain and also the amount of patients' request for painkiller injections

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: Nerve block is done by the Erector Spina Plano Block method
Category
Treatment - Drugs

2

Description
Intervention group: They will be nervously blocked by the TAP BLOCK method
Category
Treatment - Drugs

Recruitment centers

1

Recruitment center
Name of recruitment center
Shahid Beheshti Hospital
Full name of responsible person
Morteza Mohaddesh
Street address
Shahid Beheshti Hospital, Azadegan Square, Shahid Beheshti Boulevard, Qom, Iran
City
qom
Province
Ghoum
Postal code
3713649373
Phone
+98 25 3616 2651
Email
drmorteza.mohades@gmai.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Ghoum University of Medical Sciences
Full name of responsible person
Dr. Rahim Ali
Street address
Shahid Beheshti Hospital, Azadegan Square, Shahid Beheshti Boulevard, Qom, Iran
City
Qom
Province
Ghoum
Postal code
3713649373
Phone
+98 25 3616 2651
Email
drmorteza.mohades@gmai.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Ghoum University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Ghoum University of Medical Sciences
Full name of responsible person
Morteza Mohaddesh
Position
rezident
Latest degree
Medical doctor
Other areas of specialty/work
Anesthesiology
Street address
Shahid Beheshti Hospital, Azadegan Square, Shahid Beheshti Boulevard, Qom, Iran
City
Qom
Province
Ghoum
Postal code
3713649373
Phone
+98 25 3616 2651
Email
drmorteza.mohades@gmai.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Ghoum University of Medical Sciences
Full name of responsible person
Morteza Mohaddesh
Position
rezident
Latest degree
Medical doctor
Other areas of specialty/work
Anesthesiology
Street address
ShaShahid Beheshti Hospital, Azadegan Squarehid Beheshti Boulevard, Qom, Iran
City
Qom
Province
Ghoum
Postal code
3713649373
Phone
3713649373
Email
drmorteza.mohades@gmai.com

Person responsible for updating data

Contact
Name of organization / entity
Ghoum University of Medical Sciences
Full name of responsible person
Morteza Mohaddesh
Position
rezident
Latest degree
Medical doctor
Other areas of specialty/work
Anesthesiology
Street address
ShaShahid Beheshti Hospital, Azadegan Squarehid Beheshti Boulevard, Qom, Iran
City
Qom
Province
Ghoum
Postal code
3713649373
Phone
+98 25 3616 2651
Email
drmorteza.mohades@gmai.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Yes - There is a plan to make this available
Data Dictionary
Yes - There is a plan to make this available
Title and more details about the data/document
All data is potentially shareable after de-identifying individuals
When the data will become available and for how long
The access period starts 6 months after the results are published
To whom data/document is available
For researchers working in academic and scientific institutions
Under which criteria data/document could be used
Researchers working in academic and scientific institutions by sending an academic email
From where data/document is obtainable
مرتضی محدث drmorteza.mohades@gmai.com
What processes are involved for a request to access data/document
Send academic email to the researcher's email
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