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Study aim
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Clinical intervention and evaluation of the effectiveness of oral capsules containing Bonsorkh plant extract in the treatment of oxalate urinary stones.
Clinical intervention and evaluation of the effectiveness of oral capsules containing Bosorkh plant extract in the treatment of uric urinary stones
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Design
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People who meet the inclusion criteria will be randomly assigned to drug and placebo groups. The clinical trial has a control group, with parallel groups, double-blind, randomized, phase 3 on 100 patients. Simple block method was used for randomization.
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Settings and conduct
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Patients will be selected from the Nephrology of Al-Zahra Hospital (S), Noor and Ali Asghar, Isfahan. For people in the drug group, a capsule containing 500 mg of hydroalcoholic extract will be given three times a day, and for people in the placebo group, a placebo will be given.
The participants, physicians and medical personnel who are responsible for the examination and care of the patients, those responsible for data collection and those who evaluate the outcome, were kept blinded to the study groups in the study.
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Participants/Inclusion and exclusion criteria
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Inclusion criteria
Urinary tract stones
Not having a structural disorder of the urinary tract or a urinary tract infection.
No gout or hyperuricemia
Exclusion criteria
Need to be hospitalized
need for lithotripsy
UTI
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Intervention groups
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- Receiving the Bonsorkh plant for the oxalate urinary stones
- Receiving the Bonsorkh plant for the uric urinary stones
- Receiving the placebo for oxalate urinary stones
- Receiving the placebo for uric urinary stones
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Main outcome variables
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Preparation of oral capsule containing bonsorkh plant extract, clinical investigation of bonsorkh formulation in improving renal function of patients with oxalate urinary stones, clinical review of bonsorkh formulation in improving renal function of patients with uric urinary stones.