Effectiveness of repeated transcranial magnetic stimulation on sleep quality, emotional disturbance and severity of disorder symptoms in patients with emotional disorders

Determining the effectiveness of transcranial magnetic stimulation on sleep quality, emotional disturbances and the severity of symptoms of emotional disorders in patients with emotional disorders

A placebo-controlled, single-blind, randomized clinical trial of 60 patients with mood disorders. Randomized block method was used for randomization.

This study is conducted in a private clinic of psychological services in Tehran. Due to the fact that the patients do not know about the group allocation, therefore, a blind strain study is performed. We will place the patients in two groups of 30 people randomly. The experimental group will be affected by repeated transcranial magnetic stimulation and the control group will receive rTMS in silence.

Inclusion criteria: Diagnosis of emotional disorders in patients based on diagnostic criteria, age range of participants between 18 and 65 years, patients with moderate to severe symptoms, willingness to participate in research, patients with agitation Emotional and significant problems in sleep quality. Exclusion criteria: presence of coexisting psychiatric disorders, use of interfering drugs, presence of serious physical problems, presence of metal implants, pregnancy or breastfeeding, non-cooperation and unwillingness to continue the research.

60 patients with emotional disorder received repetitive transcranial magnetic stimulation (rTMS) in 20 sessions, which included frequency of 10 Hz, stimulation duration of 5 seconds, interval between each stimulation of 25 seconds, 120% movement threshold, stimulation location equal to f3 area in They receive a 10-20 system or LDLPFC and a 20-minute stimulation duration.

Sleep quality, emotional disturbances and severity of symptoms of emotional disorders in patients

In this study, patients are randomly assigned to intervention and control groups using the random block method. First, a number is assigned to each sample person. Then the numbers are written on paper, folded and thrown into a container. The papers are thoroughly mixed and removed one by one. Accordingly, one number is assigned to the first group and one number to the second group. For randomized use, one group is known as the "control group" and the other group is known as the "intervention group" by drawing lots. To randomly determine "control group" and "intervention group", we put the set of numbers of each group in two separate envelopes and put these envelopes in a container. Then we randomly take one envelope out of the container and assign it to the "intervention group" and the other envelope to the "control group". This method ensures that the allocation of patients to groups is done completely randomly and without bias.

Because the patients do not know about the group assignment, the study is performed in a blinded manner.

Since the research plan is related to a thesis, only the study protocol, clinical study report, and study results will be published. The participant data file contains information about the participants, and due to the preservation of individuals' privacy it cannot be published.

The steps of the clinical study, such as the number of participants, the inclusion and exclusion criteria for the research plan, the sampling method, the therapeutic protocol, and the study results, will be detailed in the thesis and article.

Data can be made available 6 months after results are published.

Researchers in scientific and academic centers can access the data.

In order to study or conduct research by mentioning the source.

If you need the data, write to fsohrabi.master@gmail.com.

After receiving the request and reviewing it by the main researcher, the data will be sent to the requester within a week along with an undertaking that the data will not be published without the name of the main researcher.