Protocol summary

Study aim
To Comparing Impacts of Prone and Semi-sitting Positions on Cardiac and Respiratory Indices among Patients with Chronic Obstructive Pulmonary Disease
Design
Two arm parallel group randomized trial
Settings and conduct
The research population includes all COPD outpatients who referred to Peymanieh Hospital’s clinic in Jahrom and met the inclusion criteria.
Participants/Inclusion and exclusion criteria
• Suffering from chronic obstructive pulmonary disease (COPD) • Being 18-60 years old • Being able to perform the intervention • Not having pressure ulcers on the shoulders, knees and face • Not having symptoms of increased intracranial pressure • Having no contraindications for the prone position, e.g., severe obesity, hemodynamic instability, unstable pelvic/long bone fractures, open abdominal wounds and increased intracranial pressure
Intervention groups
Patients will be taught that the head is rotated to the side and arms are positioned parallel to the body in the prone position. A towel roll is placed under the upper chest wall and a pillow is placed under the pelvis to minimize abdominal movement. Each patient will remain in this position once a day for one hour over five consecutive days at home.
Main outcome variables
HR, SBP/DBP, pao2, pco2, o2sat

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20230730058966N1
Registration date: 2024-11-14, 1403/08/24
Registration timing: registered_while_recruiting

Last update: 2024-11-14, 1403/08/24
Update count: 0
Registration date
2024-11-14, 1403/08/24
Registrant information
Name
mahdi karimyar jahromi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 71 5422 1520
Email address
mahdikarimyar310@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2024-11-05, 1403/08/15
Expected recruitment end date
2025-03-05, 1403/12/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparing Impacts of Prone and Semi-sitting Positions on Cardiac and Respiratory Indices among Patients with Chronic Obstructive Pulmonary Disease
Public title
Impacts of Prone and Semi-sitting Positions on Cardiac and Respiratory Indices among COPD
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Suffering from chronic obstructive pulmonary disease (COPD) Being able to perform the intervention Not having pressure ulcers on the shoulders, knees and face Not having symptoms of increased intracranial pressure Having no contraindications for the prone position, e.g., severe obesity, hemodynamic instability, unstable pelvic/long bone fractures, open abdominal wounds and increased intracranial pressure
Exclusion criteria:
Suffering from mental or cognitive disorders Having progressive neuromuscular disorders Having decreased level of consciousness Having unstable fractures Having deep vein thrombosis (to minimize the risk of pulmonary embolism in the prone position) Having mean arterial pressure below 65 mmHg with or without taking vasopressors Undergoing tracheal surgery or sternotomy within the past 15 days
Age
From 18 years old to 60 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 40
Randomization (investigator's opinion)
Randomized
Randomization description
The samples will randomly divided into two experimental and control groups with random number table.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Research Ethics Committees of Jahrom University of Medical Sciences
Street address
Office of Research & Technology Main Campus of Jahrom University of Medical Sciences, Motahari Blvd, Jahrom
City
Jahrom
Province
Fars
Postal code
7414846199
Approval date
2024-09-09, 1403/06/19
Ethics committee reference number
IR.JUMS.REC.1403.049

Health conditions studied

1

Description of health condition studied
COPD
ICD-10 code
J44.9
ICD-10 code description
Chronic obstructive pulmonary disease, unspecified

Primary outcomes

1

Description
Cardiac parameters (heart rate, systolic and diastolic blood pressure)
Timepoint
Before and immediately after intervention
Method of measurement
Radial pulse or monitor - mercury sphygmomanometer

2

Description
Respiratory parameters (oxygen pressure and venous CO2 - arterial oxygen saturation percentage)
Timepoint
Before and immediately after intervention
Method of measurement
Blood samples, venous blood gases - pulse oximetry

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: Prone position for one hour daily for five consecutive days
Category
Rehabilitation

2

Description
Control group: semi-sitting position at home once a day for one hour over five consecutive days
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Peymaneh Hospital of Jahrom University of Medical Sciences
Full name of responsible person
Mahdi KarimyarJahromi
Street address
Peymanyeh Hospital, Vali-Asr st. Jahrom
City
Jahrom
Province
Fars
Postal code
7414846199
Phone
+98 917 791 3060
Email
mahdikarimyar310@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Jahrom University of Medical Sciences
Full name of responsible person
Mahdi Karimyar Jahromi
Street address
Office of Research & Technology Main Campus of Jahrom University of Medical Sciences, Motahari Blvd, Jahrom
City
Jahrom
Province
Fars
Postal code
7414846199
Phone
+98 917 791 3060
Email
mahdikarirmyar310@gmail.com
Grant name
Deputy of Research and Technology of Jahrom University of Medical Sciences
Grant code / Reference number
402000130
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Jahrom University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Jahrom University of Medical Sciences
Full name of responsible person
Mahdi karimyar jahromi
Position
Assisstance professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Motahari
City
Jahrom
Province
Fars
Postal code
7414846199
Phone
+98 71 5422 1520
Email
mahdikarirmyar310@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Jahrom University of Medical Sciences
Full name of responsible person
Mahdi Karimyar Jahromi
Position
Assistance Professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Motahari
City
Jahrom
Province
Fars
Postal code
7414846199
Phone
+98 71 5422 1520
Email
mahdikarirmyar310@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Jahrom University of Medical Sciences
Full name of responsible person
Mahdi Karimyar Jahromi
Position
Assisstance Professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Motahari
City
Jahrom
Province
Fars
Postal code
7414846199
Phone
+98 71 5422 1520
Email
mahdikarirmyar310@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
No - There is not a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Yes - There is a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
Articles and other materials upon request
When the data will become available and for how long
After finishing the study
To whom data/document is available
everyone
Under which criteria data/document could be used
unconditionally
From where data/document is obtainable
Email
What processes are involved for a request to access data/document
Request by email
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