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Evaluation of the efficacy and safety of oral N-acetylcysteine in treatment and recovery of patients with COVID-19 who are under treatment with routine protocols
Study aim: Evaluation of the efficacy and side effects of N-Acetyl Cysteine in the treatment and recovery of patients with COVID-19 in Hazrat Rasool Akram Hospitals: A Randomize Clinical Trial Design: Clinical trial with control group, with parallel groups, double-blind, randomized, phase 3 on 60 patients. The rand function of the Excel software was used for randomization. Settings and conduct: Hazrat Rasool akram hospital, covid-19 admission wards randomized clinical trial Participants/Inclusion and exclusion criteria: inclusion|:hospitalized patients with moderate to severe COVID-19 with stable vital signs exclusion: Patients with unstable vital signs or need for intubation/Patients hospitalized in ICU/ history of hypersensitivity to NAC/pregnancy,lactation and infancy Intervention groups: Treatment in both control and intervention groups is based on the use of common treatment protocols in patients with covid-19. In the intervention group,oral NAC is added to the routine treatment Main outcome variables: fever/cough/dyspenia/o2 level/duration of administration/laboratory parameters/ radiologic changes/ICU admission/death
IRCTID: IRCT20200623047897N1
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