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Protocol summary

Study aim
Investigating the effectiveness of the therapist-managed smartphone application for teaching self-care activities in improving the self-care performance of children with autism spectrum disorder, their parents' participation in rehabilitation, and parent's psychosocial state
Design
Single-blind (examiner) two-arm parallel randomized controlled trial (RCT), with a four-block randomization method. The sample size was considered as 30 children with ASD and their primary caregiver.
Settings and conduct
This study will be a randomized and one-sided blind (examiner) clinical trial. The study population will include children with ASD referred to rehabilitation centers, autism centers or exceptional schools for autism in Tehran city.
Participants/Inclusion and exclusion criteria
Inclusion criteria: Having an ASD diagnosis by a child psychiatrist; The severity of autism according to the GARS test is level 1 or 2; Being a child in the age range of 5 to 12 years; According to COPM, difficulty in performing at least three self-care activities is among the main complaints of the family about the child; Being a child under occupational therapy so that self-care goals are pursued by the occupational therapist through common interventions; Ability to pay attention to images or videos on the screen for at least five minutes based on parent report; Obtaining a score above 16 in MIS in order to have the minimum ability to imitate in the use of VM; not having behavioral issues in the child based on the CSI-4
Intervention groups
In this study, the control group will receive live modeling by the main caregiver at home.The intervention group will receive the self-care activity training application to be used and practiced at home under the supervision of the therapist and researcher.
Main outcome variables
Application; self-care performance; family functioning in rehabilitation, parent's psychosocial status

General information

Reason for update
After implementing a pilot study of the using application, some changes seemed to be required to have a more concise results.
Acronym
IRCT registration information
IRCT registration number: IRCT20231124060165N1
Registration date: 2023-12-09, 1402/09/18
Registration timing: prospective

Last update: 2025-04-15, 1404/01/26
Update count: 1
Registration date
2023-12-09, 1402/09/18
Registrant information
Name
Samane Zohrabi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 41 3382 2915
Email address
samane_zohrabi@yahoo.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2024-04-20, 1403/02/01
Expected recruitment end date
2024-07-22, 1403/05/01
Actual recruitment start date
2024-04-20, 1403/02/01
Actual recruitment end date
2024-08-20, 1403/05/30
Trial completion date
2025-11-21, 1404/08/30
Scientific title
Investigating effectiveness of the therapist-managed self-care training smartphone application based on video-modeling for children with autism spectrum disorder and their parents
Public title
Investigating effectiveness of the smartphone application of training self-care activities on self-care performance of children with autism spectrum disorderو their parents’ participation in rehabilitation and psychological state
Purpose
Education/Guidance
Inclusion/Exclusion criteria
Inclusion criteria:
Having an ASD diagnosis by a child psychiatrist The severity of autism according to the GARS-3 test is level 1 or 2 Being a child in the age range of 5 to 12 years According to COPM, difficulty in performing at least three self-care activities is among the main complaints of the family about the child Participating in occupational therapy sessions so that self-care goals are pursued by the occupational therapist through common interventions. Ability to pay attention to images or videos on the screen for at least five minutes based on parent report Obtaining a score above 16 in MIS in order to have the minimum imitation ability necessary to use VM Not having behavioral issues in the child based on the child symptom inventory version 4 (CSI-4) with the subscales of attention deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder (ADHD, ODD, CD) The ability to read and write in parents of children Having an android-based smartphone
Exclusion criteria:
Existence of seizures and severe medical problems in the child based on the medical record or as reported by the parents Implementation of self-care intervention through VM in the child's current treatment plan Having a physical problem in the main caregiver
Age
From 5 years old to 12 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Outcome assessor
Sample size
Target sample size: 30
Actual sample size reached: 31
Randomization (investigator's opinion)
Randomized
Randomization description
Sampling will be done by randomization in blocks of four. Samples will be taken from the four possible blocks and until the samples are completed, they will be allocated between two control and intervention groups.
Blinding (investigator's opinion)
Single blinded
Blinding description
This study will be a randomized and one-sided blind (examiner) clinical trial.
Placebo
Not used
Assignment
Parallel
Other design features
An application with the aim of managing the training of self-care activities in children with neurodevelopmental disorders in the form of VM intervention in the android platform of the mobile phone was designed by the present researchers in the form of a technological plan that is going through the stages of construction and pilot study.

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Iran University of Medical Sciences
Street address
Iran University of Medical Sciences, Hemmat highway
City
Tehran
Province
Tehran
Postal code
1449614535
Approval date
2023-11-21, 1402/08/30
Ethics committee reference number
IR.IUMS.REC.1402.734

Health conditions studied

1

Description of health condition studied
Autism spectrum disorder
ICD-10 code
F84. 0
ICD-10 code description
A type of neurodevelopmental disorder with problems in social interactions and limited and repetitive behaviors and interests

Primary outcomes

1

Description
self-care performance
Timepoint
before intervention, immediately after the intervention, and one month after the end of intervention
Method of measurement
Activities of Daily Living Inventory for Children with Disabilities (ADLIC-D); Canadian Occupational Performance Measure (COPM); Goal Attainment Scale (GAS)

Secondary outcomes

1

Description
Family functioning in rehabilitation
Timepoint
Before the intervention, immediately after the intervention, one month after the end of intervention
Method of measurement
(FFQR) Family Functioning Questionnaire in Rehabilitation

2

Description
Depression, anxiety, and stress of parents of children
Timepoint
Before the intervention, immediately after the intervention, one month after the end of intervention
Method of measurement
Depression, anxiety, stress sacle-42 items (DASS-42)

Intervention groups

1

Description
Intervention group: In the intervention group, the first step is to install the app on the caregiver's smart phone and teach how to use it. In this training, the caregiver is asked to perform at least two activities that can be performed in the center under the supervision of the researcher, so that possible problems can be fixed and the necessary points are given feedback. In order to ensure the correctness and integrity of the training process by parents, in addition to the instruction section inside the application, a video record of app instruction will also be provided to parents. Also, in the app itself there is a guide section consistin the following sentences: The main caregiver can only use minimal physical guidance to the extent of helping the child to understand more about the correct implementation of the correct movement pattern of the desired activity.o The primary caregiver can use a cue or symbol that is familiar and meaningful to their child as an associator of the intended target activity (such as "beh beh" or "hum hum" to evoke the activity of eating) to prepare the child.o As much as possible, the training time should be in the time period close to the actual performance of that activity and based on the daily routine of that activity in a way that does not cause the child's anxiety and panic. o If according to the child's routine, the desired activity or assignment is such that it may not occur at least once during the day, create a simulator or artificial situation and practice at least once a day.o If the child does not pay attention to a part of the video or is distracted, the primary caregiver can use the repeat option to show the stage or stages of the target activity again until the child watches the videos with proper attention. Otherwise, do not use the repeat option.o It is preferable to avoid using the application when the child's attention and concentration are not suitable.o Do not use the application after taking sleeping pills. o After fully viewing all the videos related to the steps of a particular activity, the child will look at the steps step by step and after completing each step, the mother will choose the correct qualitative option and then after receiving appropriate visual feedback depending on the quality of doing it Step enters the next step.o All the steps related to a particular activity should be done in one go without a break of more than 5 seconds between the steps of the activity.o In case of three consecutive records of independently performing all steps of an activity, the caregiver can no longer use the application to perform that activity.o Avoid showing videos and applications on TV, tablets or other platforms with larger frames. Then the researcher will make the activities determined in the COPM accessible in the carer application. Caregivers will practice at home based on the training provided by the researcher and follow the guidelines and record the quality of the steps in the application. After entering the section dedicated to him in the application, the therapist will monitor the quality of the selected task that the parents mark with three options: "independent", "with help", and "dependent". The communication between the caregiver and the researcher will be done through the messaging section of the application or by calling. In case of three consecutive records of independently performing all steps of an activity, the caregiver can no longer use the application to perform that activity. The intervention process will be implemented for one to months on the intervention group. The researcher will send 3 reminder messages to the caregivers via WhatsApp. From the management panel website, the caregivers' adherence and fidelity to interventions will be implemetend.
Category
Rehabilitation

2

Description
Control group: In this study, the control group will receive live modeling by the main caregiver at home. Therapists of these samples will be asked not to use VM during the study; because after the follow-up phase, the application will also be presented to the control group. Three reminder messages a week in WhatsApp will be delivered to families. Based on logbook, the caregivers adherence to treatment will be monitored.
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
rehabilitation clinics of Rehabilitation faculty of IUMS
Full name of responsible person
Laleh Lajevardi
Street address
Rehabilitation faculty of Iran University of Medical Sciences, Madadkaran, Shahnazari, Mother square, Mirdamad
City
Tehran
Province
Tehran
Postal code
1545913487
Phone
+98 21 2222 7124
Email
laleh23275@yahoo.com

2

Recruitment center
Name of recruitment center
Parsian
Full name of responsible person
Dr. Mehdi Alizadeh
Street address
Parsian rehabilitation center, Behnam st., opposite to Tarbiyat park, Ayattollah Kashani, Sadeghiyyeh
City
Tehran
Province
Tehran
Postal code
1968633893
Phone
+98 912 307 0065
Email
mehdii.alizadeh@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Dr. Majid Safa
Street address
Iran University of Medical Sciences, next to Milad tower, Hemmat highway
City
Tehran
Province
Tehran
Postal code
1449614535
Phone
+98 21 86701
Email
Keyvanlab@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Iran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Samane Zohrabi
Position
Student
Latest degree
Bachelor
Other areas of specialty/work
Occupational Therapy
Street address
Rehabilitation faculty of Iran University of Medical Sciences, Madadkaran, Shahnazari, Mother square, Mirdamad st.
City
Tehran
Province
Tehran
Postal code
1545913487
Phone
+98 21 2222 7124
Email
samane_zohrabi@yahoo.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Samane Zohrabi
Position
Student
Latest degree
Bachelor
Other areas of specialty/work
Occupational Therapy
Street address
Rehabilitation faculty of Iran University of Medical Sciences, Madadkaran, Shahnazari, Mother square, Mirdamad st.
City
Tehran
Province
Tehran
Postal code
1545913487
Phone
+98 21 2222 2059
Email
samane_zohrabi@yahoo.vom

Person responsible for updating data

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Samane Zohrabi
Position
Student
Latest degree
Bachelor
Other areas of specialty/work
Occupational Therapy
Street address
Rehabilitation faculty of Iran University of Medical Sciences, Madadkaran, Shahnazari, Mother square, Mirdamad st.
City
Tehran
Province
Tehran
Postal code
1545913487
Phone
+98 41 3382 2915
Fax
Email
samane_zohrabi@yahoo.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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