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. rehabilitation in patients with Covid-19. Design: This study is a single-blind, two-armed parallel randomized (...) group, the same program will be performed for patients with Covid-19 who are candidates for the (...) : Inclusion: 1- Patients who were diagnosed with Covid-19 and discharged from the hospital. 2- Patients aged
IRCTID: IRCT20220103053609N1
Study aim: To study the effectiveness of the formulated capsule containing the extract of Hypericum p. and Melissa o., with deuterium depleted water, in patients with covid-19 who volunteer at the (...) following: clinical signs indicative of Covid-19 including fever, dry cough, shortness of breath, CT scan
IRCTID: IRCT20210216050373N2
human umbilical cord matrix-derived mesenchymal stem cell injection in the treatment of new COVID-19 (...) controlled clinical trial study design. The sample size of the study is 60 COVID-19 patients that are (...) : This study is performed to decrease the mortality and other complications of patients with COVID-19 and
IRCTID: IRCT20211012052743N1
Study aim: Introducing a more effective treatment protocol to increase blood oxygen level, prevent disease progression, improve respiratory tidal volume and lung function in Covid 19 patients. Design: Two (...) exclusion criteria: Inclusion criteria: 35 to 75 years old patients, affected by Covid 19, consciousness, in
IRCTID: IRCT20210505051181N2
with COVID-19 Design: This double-blind, phase 2 clinical trial is performed in 60 patients with symptomatic COVID-19. Patients are randomly assigned to 30 blocks of 2 patients. Each patient in the block (...) : Sixty eligible patients with covid-19 pneumonia referred to Sabzevar medical college Hospital will be
IRCTID: IRCT20080901001157N17
  1. Evaluation of the effect of IMFLUNA herbal compound on the improvement of covid-19 pneumonia symptoms in patients referred to Baqiyatallah Hospital
  2. Evaluation of safety and efficacy of IMPOHelzavid herbal compound on improving the symptoms and complications of patients with community acquired pneumonia
  3. Investigation of safety and efficacy of GLARTA herbal syrup on improving the symptoms and complications of patients with pneumonia
  4. Effect of Silybum marianum, Melissa officinalis, Vaccinium arctostaphylos, Trigonella foenum, Urtica dioica, and Citrullus colocynthis extract mixture on blood sugar control in type 2 diabetic patients
  5. Effect of Trigonella foenum-graecum, Vaccinium arctostaphylos, Cichorium intybus, Urtica dioica and Curcuma longa extracts mixture on blood sugar control in type 2 diabetic patients
  6. Effect date seed (Phoenix dactylifera L) coffee extract on blood sugar control in type 2 diabetic patients
  7. Comparison of the effectiveness of oral syrup and intranasal spray of Falcaria Vulgaris plant on patients with Covid-19
  8. Evaluation of the effectiveness of Silymarin (Silybum marianum) capsule on the clinical symptoms of outpatients with COVID-19
  9. Evaluation of the effectiveness of herbal mixture based on Boswellia in improving cognitive and behavioral disorders in patients with mild to moderate Alzheimer's disease ,A Randomized Double-Blind Clinical Trial with Placebo-Controlled.
  10. Evaluation of the effectiveness of complementary therapy with Basil (Ocimum basilicum) capsule on the clinical symptoms of outpatients with COVID-19
Study aim: Effect of Hemoperfusion on short term survival of critical ill COVID-19 patients (...) and conduct: Patients with Covid 19 admitted to the ICU of Imam Reza Hospital will be randomly (...) criteria: Inclusion criteria: Patients 18 to 75 years of age with Covid 19 Absence of active bleeding
IRCTID: IRCT20091012002582N22
supplements on the improvement of clinical symptoms associated with COVID-19. Design: The clinical trial (...) have referred to Shariati Hospital with a positive chest CT scan for COVID-19 will be selected. After (...) be received, daily. The control group will receive only routine Covid-19 treatment. Participants
IRCTID: IRCT20201004048923N1
  1. The effect of vitamin C and E in the treatment and clinical course of patients with SARS-cov2 (COVID-19)
  2. Effect of Intravenous immunoglobulin (IVIG) versus Kaletra (lopinavir and ritonavir) tablets in patients with acute respiratory infection (COVID-19): A clinical trial studies
  3. Evaluation of the effectiveness of intravenous infusion of human COVID-19 hyperimmune plasma with specific antibody titer in hospitalized patients with Covid-19: a randomized clinical trial
  4. Comparison of The Therapeutic Effect of Convalescent Plasma and Plasma-derived Immunoglobulin-enriched solution on COVID-19 Patients: A Clinical Trial Study
  5. The effect of inhalation of orange peel and peppermint extract on reducing the severity of COVID-19 symptoms in patients referred to clinic with a positive result of lung CT scan
  6. The role of colchicine in the treatment of covid-19 patients hospitalized in the intensive care unit
  7. effect of Hesperidin,Artemisinin- Artemisia annua, Noscapine, N-acetylcysteine, Resveratrol supplements and high dose of vitamin C on treatment, clinical symptoms of non-hospitalization and hospitalization patients with symptomatic COVID-19
  8. Interventional study of intravenous vitamin C in definitive patients with covid 19 and its effect on changes in lung CT scan and clinical and laboratory symptoms of patients
  9. evaluation of the effects of the 2-drug diet (hydroxychloroquine + umifenovir(Arbidol)) compared with Hydroxy chlorquine on the of mortality rate in patients with moderate symptoms of COVID-19 infections: A randomized interventional study in Imam Reza Hospital, Mashhad.
  10. Investigating the effect of Medical Beer on the fever of patients with COVID-19
Study aim: Considering that COVID-19 is associated with high morbidity and mortality and high (...) COVID-19 who have been referred to Ziaian, Imam Khomeini and Baharloo hospitals, after examination by a (...) Medical Centers proven cases of COVID-19 After obtaining informed written consent consciously, they are
IRCTID: IRCT20180922041089N4
  1. The efficacy and safety of Ivermectin in patients with COVID-19: a randomized clinical trial
  2. The effect of cognitive-behavioral crisis intervention package on improving COVID-19 fear symptoms, improving quality of life and improving mental health in patients with corona
  3. Dose-Finding study of Ivermectin treatment on patients infected with Covid-19:A clinical trial
  4. Determination the therapeutic effect of Ivermectin and Sovodak on patients infected with COVID-19: A clinical trial.
  5. The effect of cognitive-behavioral intervention in reducing fear of COVID-19 symptoms, anxiety, depression, stress and improving the quality of life in people suffering from prolonged grief disorder due to the COVID-19
  6. The effect of combined regimen of ivermectin and fluoxetine on the prevention of hospitalization and amelioration of symptoms in mild covid-19 patients
  7. To study the effect of Metronidazole and Ivermectin in the recovery of the infected patients with COVID-19 compared with protocol treatment: triple-blind randomized clinical trial
  8. Evaluating efficacy of Kelofan syrup, a traditional Iranian medicine product on pulmonary & other clinical and laboratory manifestations of patients with or probable of covid-19
  9. Evaluating efficacy of Kelofan syrup, a traditional Iranian medicine product, on pulmonary and other clinical and laboratory manifestations of patients with probable or confirmed COVID-19
  10. Comparative evaluation of the efficacy of acupuncture and warm cupping on clinical manifestations of patients with COVID-19
ambulatory patients with COVID-19 Design: Randomized, placebo-controlled, quadruple blind multicentre (...) community clinics designated for COVID-19 patients according to the national protocols of the ministry of (...) history of COVID-19 2. Pregnancy or breastfeeding 3. Known severe chronic kidney disease requiring
IRCTID: IRCT20200831048568N1
markers in critical ill patients with COVID-19 Design: A randomized clinical trial study, triple-blind trial, fifty critical ill patients infected with COVID-19 undergoing respiratory and nutritional (...) exclusion criteria: This study will be done on fifty critical ill patients with COVID-19 who are undergoing
IRCTID: IRCT20151226025699N3
  1. The effect of vitamin A, B, C, D, and E supplementations on biochemical parameters of critically ill patients with COVID-19: A randomized clinical trial
  2. Comparison of the effectiveness of omega-3 and Hydroxychloroquine on Inflammatory factors, liver enzymes and clinical symptoms in diabetic COVID-19 patients
  3. Evaluation of Hemoperfusion effect in treatment of patients with COVID-19 hospitalized in intensive care unit, Randomized clinical trial
  4. An international randomised trial of additional treatments (Arttesunate, Infliximab, Imatinib) for COVID-19 in hospitalised patients who are all receiving the local standard of care
  5. Effect of Concomitant Synbiotic and L-Carnitine Supplementation on Nutritional Status, Metabolic, Oxidative, Inflammatory Indices and Plasma Levels of Trimethylamine Oxide (TMAO) in Obese Women
  6. Effectiveness evaluation of Tofacitinib plus Remdesivir in comparison with Remdesivir in the treatment of adult patients with severe COVID-19 A randomized double-blind placebo-included clinical trial
  7. The effect of Omega-3 supplementation on Inflammatory biomarkers and total Blood cell counts of Patients with Covid-19
  8. Evaluation of the effects of rice bran oil capsule on glycemic indices, antioxidant and inflammatory indicators patients with type 2 diabetes: Double-blinded randomized clinical trial
  9. Study of Ivermectin Effectiveness in treatment process, survival and cure rate of COVID-19 patients: a randomized clinical trial
  10. Investgation of the effect of Curcumin and/or omega-3 polyunsaturated fatty acids supplementation on anthropometric indices, glucose hemostasis, markers of cardiometabolic risk and gene expression of vascular endothelial growth factor and serum concentrations of inflammatory and oxidatve stress indices in type 2 diabetic patients
patients with covid-19 pneumonia Design: This double-blind, phase 2 clinical trial is performed in 60 patients with covid-19 pneumonia. Patients are randomly assigned to 30 blocks of 2 patients. Each patient (...) conduct: Sixty eligible patients with covid-19 pneumonia referred to Baqiyatallah Hospital will be
IRCTID: IRCT20080901001157N16
, Foeniculum vulgare and a small amount of opium in patients with COVID-19. Design: This study is a clinical (...) covid 19 based on laboratory confirmation the probable diagnosis of covid 19 based on respiratory
IRCTID: IRCT20200411047016N1
  1. The effect of Zataria multiflora boiss capsule on postpartum pain
  2. The effect of Zataria multiflora Boiss in the treatment of non alcoholic fatty liver disease
  3. Comparison Efficacy of extract plants of Zingiber , cinnamon , zataria multiflora with standard protocol in treatment and clinical improvement of patients with moderate to severe symptoms of covid-19
  4. Clinical assessment of herbal inhalation of Hydroalcoholic Extract of lavender, Coriandrum sativum, Zataria multiflora, Mentha piperita, in treatment of Sinus Headache: A Randomized Double Blind Clinical Trial
  5. Comparison of Eeffect of Zataria Multiflora Boiss Vaginal Cream with Clotrimazol Vaginal Cream in Candida Vaginitis Treatment
  6. Evalution of the effect of combination therapy with extract of Bunium Persicum and Foeniculum Vulgare on clinical features in Polycystic Ovary Syndrome (PCOS) patients
  7. the effect of Heracleum persicum hydroalcoholic extract on hot flashes in menopausal women
  8. The comparative effects of the mouthwash containing Zataria multiflora essence 2% and chlorhexidine 0.2% on the prevention of ventilator-associated pneumonia in patients admitted to intensive care units
  9. Efficacy of herbal drug that is composed of essential oil of Zataria multiflora Boiss, Trachyspermum ammi and Anethum graveolens L, in treatment of Irritable bowel syndrome (IBS).
  10. Comparison of efficacy of two traditional medicine, Zataria multiflora Boiss and trachyspermum Copticum (L.) Link, on Clinical symptom in patient with Irritable bowel syndrome (IBS)
group: Using the Hyssop and Verbascum herbal tea three times a day for patients with Covid 19 disease (...) -19 Design: Clinical trial with control group، Community-based and forward-looking، With parallel (...) sections. Main outcome variables: Improving the symptoms of Covide-19 disease.
IRCTID: IRCT20100130003227N15
Study aim: The effect of Trehala Manna on inflammatory biomarkers and clinical symptoms in covid-19 (...) informed consent Covid-19 patients (PCR positive test or clinical symptoms such as fever > 38, respiratory rate ≥ 24, dry cough, myalgia, asthenia, anosmia, and or anorexia Admission to general corvid-19 unit
IRCTID: IRCT20211029052904N1
Study aim: Evaluation of the therapeutic effect of Remdesivir on covid-19 patients referring to (...) hospital, Evidence of multiple organ failure, Receive any experimental treatment for Covid 19, Patients (...) prepared with 19 cc of distilled water and diluted with 0.9% saline. Main outcome variables: Long of stay
IRCTID: IRCT20200404046937N5
Study aim: Safety and immunogenicity of Covid 19 FAKHRAVAC (MIVAC) inactivated vaccine in healthy (...) current or previous COVID-19 infection; Use of safe methods of contraception; Signing informed consent (...) -risk occupations exposed to Covid-19; serving in obligatory military service; Breastfeeding; Pregnancy
IRCTID: IRCT20210206050259N2
  1. Phase 1, safety, immunogenicity and dose finding for two strengths of 0.5 × 10^6 and 2.5 × 10^6 (TCID50) inactivated SARS-CoV-2 vaccine FAKHRAVAC (MIVAC) injected in two schedules of two doses, 2 and 3 weeks apart in healthy adults aged 18-55 years: a randomized, double blind, placebo controlled, clinical trial
  2. Comparison of safety and immunogenicity of FAKHRAVAC and Sinopharm booster doses for adults 18 years of age and older, fully vaccinated by Sinopharm: a ‎parallel ‎‏2‏‎ arms, ‎randomised, double blind clinical trial
  3. Comparison of the safety and efficacy of Fakhravac and Sinopharm SARS-CoV-2 vaccines, in adults aged 18 and over; a phase III randomized, non-inferiority clinical trial
  4. Phase II, Safety and Immunogenicity of RAZI SARS-CoV-2 recombinant Spike protein vaccine (RAZI Cov Pars) in adults aged 18-70 years; a Randomised, double blind, parallel 2 arms clinical trial
  5. Safety and Immunogenicity of Razi Cov-2 recombinant Spike protein vaccine (RAZI Cov Pars) in healthy children and adolescents aged 5-17 years; single group, open label study
  6. Phase I, Safety and Immunogenicity of Razi SARS-CoV-2 recombinant Spike protein vaccine (Razi Cov Pars), in healthy adults aged 18-55 years; parallel 4 arms design (adjuvant only and three vaccine doses of 5, 10, and 20 µg/200µl); a Randomised, double blind, clinical trial
  7. A Clinical trial to evaluate the immunogenicity and safety of Omicron-Based CovIran Barkat vaccine as a third injection dose in vaccinated population over 18 years of age
  8. Immunogenicity and safety of pastocovac vaccine as a booster dose in comparison with sinopharm and pastocovac Plus boosters in Iranian adults aged 18 to 80 who received 2 doses of Sinopharm vaccine: a parallel group clinical trial
  9. Comparison of immunogenicity and safety of Razi Cov Pars and Sinopharm booster doses in adults 18 years of age and older who have primarily vaccinated with Sinopharm: a ‎parallel ‎‏2‏‎ arms, ‎randomised, double blind clinical trial ‎
  10. Evaluation of SARS-CoV-۲ Vaccine (Pastocovac) effectiveness and serologic response in Patients Receiving Hematopoietic Autologous Stem Cell Transplantation compared to control group: A clinical trial
Study aim: Main Aim: To evaluate the safety and efficacy of medications in treating COVID-19 Specific Aims: -To evaluate the safety and efficacy of Remdesivir in treating COVID-19 -To evaluate the safety and efficacy of Chloroquine/Hydroxychloroquine in treating COVID-19 -To evaluate the safety and
IRCTID: IRCT20200405046953N1
patients with COVID 19 Design: Clinical trial with control group, with parallel groups, double blind (...) hospitalization in the COVID-19 support ward, video calls in the morning, evening and night shifts between the (...) family's smartphone at home. Participants/Inclusion and exclusion criteria: Inclusion criteria: COVID-19
IRCTID: IRCT20180429039463N4
  1. The effect of planned online video meeting on anxiety, depression and satisfaction of patients in the open heart intensive care unit
  2. The effect of online group support on psychological distress and self-care behaviors of the elderly with type 2 diabetes during the COVID-19 pandemic: a parallel randomized clinical trial
  3. The effect of the Video communication between patient and family member on hospital anxiety and depression of of affected patients with COVID-19 and perceived stress of family member
  4. Comparing of the Effect of Supportive Educative Program with Routine educative program on Stress, Anxiety, Depression and Satisfaction of Patients With COVID-19 Admitted to COVID units
  5. The effect of the web- based communication between nurse and family member on perceived stress of family member of suspected and affected patients with COVID-19
  6. The effect of multimedia-based peer support groups on anxiety in patients with COVID-19: a parallel randomized clinical trial
  7. Effect of Internet- Based Psychoeducational Support on Perceived Stress and Caring Burden in Caregivers of Patients with COVID-19
  8. Effect of Stress Management Program on Psychological Distress of Cancer Patients and Caring Burden and Quality of Life of Their Caregivers during the COVID-19 Epidemic
  9. The effect of supportive role of nurse on stress, anxiety and depression in the hospitalized elderly with COVID-19 in Firoozabadi hospital at Rey city
  10. The effect of scheduled Visitation on the components of mental health of the families whose patients have undergone open heart surgery
multiflora with standard treatment in adult patients with moderate to severe symptoms of Covid 19 Design: In (...) intervention of that group. Settings and conduct: Adult patients with Covid 19 are randomly assigned to one of (...) allergy. Intervention groups: According to the National Protocol,patients with Covid-19 in addition to
IRCTID: IRCT20081011001323N25
drugs, respectively, and all intervention and control groups will receive COVID 19 standard treatment (...) receive standard treatment of Covid 19 based on the Ministry of Health guidelines (dexamethasone (...) Study aim: Determining the effect of DPP4 and spironolactone inhibitors in the treatment of COVID
IRCTID: IRCT20201003048904N2
  1. Evaluation of the protective effect of a combination drug including Apocynin, Niacin, and Tannin on prevention of cardiovascular and respiratory morbidities and mortality in COVID-19 infection: A Clinical Trial
  2. Evaluation of short term outcomes of liver transplantation from COVID-19 positive deceased donors
  3. Application of Methylene Blue Along with Complementary Materials for Treatment of COVID-19 Outpatients with Less Than 8 Days from First Day of Clinical Symptoms
  4. Comparison of the effect of high-pressure nasal cannula and conventional oxygen treatment in Covid-19 patients referred to the emergency department
  5. Evaluation of the Effect of Methylene Blue with Supplements in the Treatment of Patients with Moderate to Severe Outpatient COVID-19 Infection in Comparison with the Control Group
  6. Evaluation of the Effect of Blood Transfusion on the Atrial Blood Oxygen Saturation percentage in COVID-19 patients
  7. Evaluation the efficacy and safety of Sitagliptin administration in patients with COVID-19
  8. Evaluating the effectiveness of adding probiotic supplements to standard treatment in the treatment process of pregnant women with COVID-19: a double-blind randomized clinical trial
  9. A prospective randomized controlled trial comparing the effectiveness of traditional medicine combination based on the Ferula assa-foetida gum - Tragacanth with moderate to severe Coronavirus disease (COVID-19) compared to standard treatment
  10. Study of the effect of dipeptidyl peptidase 4 inhibitors on the improvement rate and prognosis of diabetic patients with Covid-19
Study aim: Study of the safety of hyperimmune bovine milk and colostrum against Covid-19 Design (...) Criteria Signing consent form of the study Free of underlying disease Not having clinical signs of Covid-19 infection -Exclusion Criteria Diseased person infected by Covid-۱۹ or other diseases having underlying
IRCTID: IRCT20200927048849N1
  1. Comparison of the Effectiveness of COVID-19 specific antibody in hyperimmune bovine milk & colostrum with ordinary bovine milk & colostrum in improving clinical symptoms and laboratory parameters and outcomes of patients with COVID-19 admitted to Hospital
  2. Comparison of the Effectiveness of COVID-19 specific antibody in hyper-immune bovine milk & colostrum with ordinary bovine milk & colostrum on reducing the need for hospitalization and improving clinical symptoms of patients with COVID-19 that are taken care of in home.
  3. "The effect of enteral bovine colostrum supplement on outcomes of critically ill patients with acute respiratory failure
  4. Investigating the comparative preventive efficacy and safety of FluGaurd® (a 4-valent recombinant influenza vaccine, produced by Niwad-Pharmed-Salamat company, I.R.Iran), to Vaxigrip® (produced by Sanofi company, France) as the reference product in Healthy volunteers
  5. Evaluation of SARS-CoV-۲ Vaccine (Pastocovac) effectiveness and serologic response in Patients Receiving Hematopoietic Autologous Stem Cell Transplantation compared to control group: A clinical trial
  6. Safety and immunogenicity of SARS-CoV-2 inactivated vaccine (OSVID-19) in healthy volunteers aged 18 to 40 years: A clinical trial, phase 1, single arm
  7. Evaluation of the effect of FLUVAR® in respiratory dosage form on the prevention of COVID-19 respiratory infection
  8. Evaluation of the effectiveness of intravenous infusion of human COVID-19 hyperimmune plasma with specific antibody titer in hospitalized patients with Covid-19: a randomized clinical trial
  9. Evaluation of the effect of Ionic Plasma Cluster Technology on the improvement of symptoms in patients with COVID-19
  10. Evaluation of the immunogenicity and safety of quadrivalent flu vaccine (Fluguard) manufactured by Nivad pharmed Salamat, in comparison with seasonal flu vaccine Vaxigrip, as a reference product made by Sanofi, France in healthy volunteers aged 18 to 49 years, study Clinical phase 3 random, double-blind, double-arm, parallel, active control, non-inferiority
program , A positive covid 19 polymerase chain reaction test with at least one of the following (...) Study aim: Evaluation of the effectiveness of Thiamine-Ascorbic acid-Methylprednisolone (TAM) cocktail in the treatment of critically ill patients with Covid-induced pneumonia. Design: Open-labeled
IRCTID: IRCT20200415047080N2
  1. The effect of combination of selenium, vitamin C and methylprednisolone in acute respiratory distress syndrome mortality and morbidity from COVID-19
  2. Comparison of Bactiguard endotracheal tubr to Taperguard endotracheal tube in decreasing ventilator associated pneumonia in critically ill patients admitted to intensive care unit
  3. Evaluation of high-dose anti-inflammatory effects of l-carnitine in patients with critical ill in the intensive care unit
  4. Clinical trial of ealuation of phage therapy with nebulizer in prevention of secondary bacterial pneumonia in admitted patients with moderate to severe COVID-19
  5. Evaluation of the effectiveness of intravenous infusion of human COVID-19 hyperimmune plasma with specific antibody titer in hospitalized patients with Covid-19: a randomized clinical trial
  6. Evaluation of phage therapy in prevention of bacterial pneumonia caused by ventilator in patients admitted to Pediatric Intensive Care Unit of Buali Hospital of Sari
  7. Evaluation of the effect of IMFLUNA herbal compound on the improvement of covid-19 pneumonia symptoms in patients referred to Baqiyatallah Hospital
  8. Evaluating the efficacy and safety of Adalimumab in patients with acute respiratory distress syndrome caused by COVID-19
  9. Comparison of the efficacy and safety of Atazanavir/Ritonavir plus Hydroxychloroquine regimen with Lopinavir/Ritonavir plus Hydroxychloroquine regimen in patients with moderate COVID-19, A randomized, double-blind study
  10. Comparison of fixed and individualized regimen of vancomycin in achievement to recommended blood concentration based on clinical guidelines in critically ill patients.
shortness of breath and fatigue in patients with Covid-19 Design: A randomized controlled clinical trial (...) have the highest admission of patients with Covid-19 will be prepared and randomized. Blocks are (...) . Participants/Inclusion and exclusion criteria: Inclusion criteria include: (1) Patients with Covid-19 (2) Age
IRCTID: IRCT20210717051910N1
clinical trial in Shariati hospital on patients with severe COVID-19 who are over 18 years of age and hospitalized. Participants/Inclusion and exclusion criteria: Patients with a definitive diagnosis of COVID-19 (...) Study aim: Evaluating the efficacy and safety of Adalimumab (CinnaGen Co.) in patients with COVID
IRCTID: IRCT20150303021315N22
  1. The evaluation of safety and efficacy of Pembrolizumab (CinnaGen Co, Iran) in patients with COVID-19
  2. Evaluating the efficacy and safety of Adalimumab in patients with acute respiratory distress syndrome caused by COVID-19
  3. A phase Ш, randomized, two-armed, double-blind, multicenter, parallel, active-controlled, non-inferiority clinical trial to compare efficacy and safety of guselkumab (CinnaGen co) versus Tremfya® (Janssen co) in patients with moderate to severe plaque psoriasis
  4. A single armed, open label, clinical trial to evaluate the immunogenicity of SpikoGen® vaccine as booster dose (Spike protein, produced by CinnaGen company) in kidney transplant patients being fully vaccinated with Sinopharm vaccine
  5. A phase III, randomized, multicenter, double-blind, two-armed, parallel, active-controlled, non-inferiority clinical trial to compare efficacy and safety of Evolocumab (CinnaGen) versus Evolocumab (Repatha®, Amgen Inc.) in patients with hyperlipidemia receiving concurrent high intensity statin
  6. Evaluation of the efficacy and safety of Adalimumab and methylprednisolone pulse therapy in treatment of Covid-19 patients with ARDS
  7. A phase III, Randomized, Two-armed, Double-blind, Placebo controlled trial to evaluate efficacy and safety of an adjuvanted recombinant SARS-CoV-2 spike (S) protein subunit vaccine (SpikoGen®) produced by CinnaGen Co. (Two doses of 25µg with dosing interval of 21 days)
  8. A randomized, two-armed, Placebo controlled (5:1), Double-blind, parallel clinical trial to compare the immunogenicity and safety of SpikoGen® vaccine (an adjuvanted recombinant spike (S) protein produced by CinnaGen Co.) as a booster dose
  9. A Phase III, randomized, two-armed, double-blind, ‎parallel,active-controlled, clinical trial to evaluate equivalency of the efficacy and safety of Ocrelizumab (CinnaGen, Iran) in comparison to reference product, Ocrevus® (Roche, Switzerland) in patients with relapsing multiple sclerosis
  10. Safety and Efficacy of CinnaGen Human Recombinant Growth Hormone in Comparison with Novo Nordisk Growth Hormone in Children with Idiopathic Growth Hormone Deficiency: A Randomized Clinical Trial
with confirmed COVID-19 diagnosis (RT-PCR positive) and severe lung involvement (oxygen saturation < 90
IRCTID: IRCT20151227025726N27
  1. The effect of IL-6 inhibitor (Tocilizumab) on the prognosis of covid-19 patients with acute respiratory failure
  2. Comparisson of the effectiveness of Tocilizumab and Tofacitinib on the outcomes of patients with severe COVID-19
  3. Evaluation of the safety and efficacy of tocilizumab (AryoGen ‎Pharmed Co., Iran) in patients with severe COVID-19‎
  4. Efficacy of Tocilizumab in Hospitalized Patients with COVID-19: An open-label placebo-controlled clinical study
  5. Evaluation the Efficacy and Safety of Tocilizumab in Patients with Novel Coronavirus (COVID-19)
  6. Comparison of the effect tocilizumab, plasmapheresis and tocilizumab plasmapheresis combination in Coronavirus disease (COVID -19) patients admitted to the intensive care unit
  7. Comparison of the efficacy and safety of Atazanavir/Ritonavir plus Hydroxychloroquine regimen with Lopinavir/Ritonavir plus Hydroxychloroquine regimen in patients with moderate COVID-19, A randomized, double-blind study
  8. Evaluation of The effect of Tocilizumab on the recovery rate of patients with severe Covid 19 disease referred to Razi Hospital in Ahvaz
  9. Multicenter, Open-Label, Phase IV Study to Evaluate the Safety,Tolerability, and Efficacy of Tocilizumab in Patients with Active Rheumatoid arthritis on background non-biologic DMARDs who have an inadequate response to current non-biologic DMARD and/or Anti- TNF therapy
  10. Phase I clinical trial using ex vivo-expanded allogeneic donor-derived NK cells in patients with lower respiratory disease (Moderate) caused by COVID-19.
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