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Study aim:
Determining the mortality rate of patients during hospitalization in both groups of pulse methylprednisolone group and 1 mg/per kiloogram of body weight every 12 hours.
Design:
The trial has two study groups in parallel, randomized, non-blind phase 3 on 74 patients and uses rand function of excel for randomization
Settings and conduct:
Patients with mild to moderate acute respiratory distress syndrome who admit to corona ward of Loghman Hakim hospital will go under study with two different regimen of methylprednisolone doses.
Participants/Inclusion and exclusion criteria:
inclusion criteria:
Patients older than 18
Patient with severe acute respiratory injury with symptoms of novel coronavurus during 10 recent days
Posotive polymerase chain reaction (PCR) test of novel coronavirus or chest CT scan that confirms coronavirus pneumonia
Mild to moderate acute respiratory distress syndrome
No more than 24 hours have passed since their admission.
The patient should not be under invasive mechanical ventilation when entering the study.
Satisfaction to participate in the study.
Exclusion criteria:
Dissatisfaction of the patient or the patient's legal companion.
Pregnancy and lactation.
Chronic hemodialysis
Heart failure
Severe vasoplegic shock
Pulmonary edema due to other pathology like heart failure , cirrhosis , chronic kidney failure
Severe hypoxemia
If patient expires lower than 3 days after beginning of treatment.
Intervention groups:
One group recieves 1 mg per kg of methylprednisolone every 12 hours and other one recieve 1000 mg of methyl prednisolone daily for 3 days then keep on with 1 mg per kg every 12 hours.
Main outcome variables:
mortality ratio
patients with COVID-19 and its effect on pneumonia manifestations and clinical and laboratory symptoms of (...)COVID-19 pneumonia. Eligible patients with the same diet and underlying disease are divided into control (...)
Intervention groups:
In this study, patients with PCR confirmed COVID-19 are examined. First, patients who meet
COVID-19
To determine the effect of Ivermectin on the recovery of patients infected with COVID-19
To compare the effect of Ivermectin and Metronidazole in the recovery of patients infected with COVID-19(...) 18 years and older with positive Covid-19 test (infection would be confirmed by RT-PCR or CT-scan
Study aim:
Determining the effect of environmental health education program on self-efficacy and anxiety caused by Covid-19 in nurses
Design:
Superiority clinical trial, randomized controlled trial in (...) than one absence from training sessions, occurrence of severe stressful events, Covid-19
Inclusion
Study aim:
The aim of this study was to evaluate the effect of nano-solution in inhaled form using a nebulizer to prevent the development of infection in lung tissue and increase the respiratory capacity of patients with Covid-19.
Design:
A clinical trial with a control group, with parallel, blind
laboratory and radiological findings and short-term results of patients with COVID-19
Design:
This study is (...) understand their group (group A or B)
Settings and conduct:
This study is performed on COVID-19 patients with vitamin D deficiency in the COVID-19 ward of Imam Hossein Shahroud Hospital in two groups of
Study aim:
To determine the tolerability, safety, and immunogenicity of COVID-19 inactivated (...) events, and COVID-19 incidence.
Participants/Inclusion and exclusion criteria:
Main inclusion criteria (...) PCR test, Previous history of infection, symptoms consistent with COVID-19, history of close contact
Study aim:
Effect of high dose of vitamin D on mortality, length of stay and inflammatory markers on Covid19 patients admitted in the intensive care unit
Design:
A parallel, double-blind, placebo controled, randomized clinical trial
Settings and conduct:
This study will be done on 60 corona virus
with chloroquine in patients with COVID-19 In terms of the outcome including mortality, transference to (...)
comparison with chloroquine in patients with COVID-19 In terms of the hospitalization duration
3. Evaluation (...) with COVID-19 In terms of the cessation of fever
Design:
clinical trial, blinded, phase III, with
factors in patients with
Covid19
Design:
This study is a randomized, double-blinded, controlled (...) with Covid-19 will be going to Persian Gulf Hospital, Bushehr, Iran, to do the PCR test and the (...) exclusion criteria:
Inclusion criteria: Age above 18 years. Having Covid -19, Lung involvement approved by
Study aim:
To determine the safety and immunogenicity of COVID-19 inactivated vaccine in a healthy (...) : Positive PCR test, previous history of infection (positive antibody), symptoms consistent with COVID-19, history of close contact with COVID-19 patient in the last 14 days, abnormal paraclinical findings
between 18 to 70 years
2- COVID-19 confirmed patients on 10 liters of oxygen or more.
Exclusion criteria (...) ventilation) in hypoxemic patients with CVOID-19 infection requiring at least 10 liters of oxygen.
Design (...) be conducted in the department of General Medicine in the specialized COVID isolation units. This is
Study aim:
valuating the Safety and Effectiveness of Septimeb in Patients with COVID-19
Design:
Clinical trial with control group, without blinding, randomized by simple randomization on 240 patients (...) LDH and increased D-DIMER test
Exclusion Criteria:
No COVID-19 PCR test
Drug users - Alcohol
clinical symptoms, inflammatory markers, and oxidative stress in patients with Covid-19.
Design:
This (...) with Covid-19 admitted to the Shahid Mohammadi hospital in Bandar Abbas city that be eligible for (...)Covid-19 by RT-PCR test, completing informed consent, less than 48 hours have passed since the patient
, thorax and diaphragm on respiratory function and tolerance in patients with Covid-19.
Design:
Fifty patients with Covid-19 are divided into two intervention groups and the control group (simple randomization (...) respiratory function and tolerance of patients with Covid-19 hospitalized in the wards. The study will be
Study aim:
Determination of the effect of 5% hypertonic saline on inflammatory mediators in patients with severe pneumonia caused by Covid-19 admitted to ICU
Design:
This study is a randomized (...) : Patients with severe pneumonia caused by Covid-19 admitted to the ICU, age between 18-70 years old
Study aim:
Evaluation of short-term effects of Celecoxib on clinical improvement of COVID-19 patients: A randomized clinical trial study
Design:
Based on the treatment chart and matching of the studied individuals and in order to eliminate any confounding factor, receiving all kinds of main and
coltra in the treatment and improvement of symptoms in patients with Covid19 will be evaluated.
Design (...) Dr.Ganjavian Hospital in Dezful in patients who have received the covid -19 treatment regimen in accordance (...) years of age whose covid-19 disease has been confirmed by PCR test and clinically severely ill.
o2sat
Settings and conduct:
People with Covid-19 admitted to Shahid Sadoughi Hospital in Yazd were divided into (...) .
Participants/Inclusion and exclusion criteria:
Inclusion criteria: age between 18- 80 years old, Covid-19(...) interferon and methylprednisolone in comparison with beta interferon on the recovery of patients with Covid
COVID-19
Design:
Prospective clinical trial with parallel randomized control and treatment, double (...) : 100 patients with COVID-19, using block randomization will be divided in to intervention and control (...) laboratory (RT-PCR) confirmed infection with COVID-19 and lung involvement confirmed with chest imaging will
paraclinical symptoms of COVID-19 patients.
Design:
A randomized controlled, triple blinded clinical trial (...) be conducted on COVID-19 patients who referred to Imam Reza and Sinai Educational-Medical Center (...) this study, all patients aged 15 years and older with COVID-19 who had newly admitted to the hospital
the primary and secondary outcomes of COVID-19 infection in affected patients.
Design:
double blind, randomised controlled trial
Settings and conduct:
The project will perform in Sina hospital as a COVID-19 center.
Subjects including patients with positive COVID-19
Participants, physicians, data collectors
Study aim:
Dose finding of Ivermectin in control and treatment of COVID-19 patients and suggesting it as an antiviral drug against COVID-19
Design:
clinical trial with control group, with parallel (...) /Inclusion and exclusion criteria:
1. Patients who test positive for COVID-19 by a commercially available
Study aim:
Comparison of the administration of vitamin D3 and N acetylcysteine tablets in COVID-19(...) Ayatollah Taleghani Hospital in Abadan. The study was performed on 100 patients with COVID-19 who were (...) /Inclusion and exclusion criteria:
Inclusion criteria: COVID-19 patients that have positive PCR test of
Study aim:
Determining the effectiveness of midwifery counseling in a "supportive" way on stress and anxiety caused by the Covid19 epidemic in pregnant women.
Design:
This study is a parallel (...) outcome variables:
Covid19 stress and anxiety in pregnant women.